Plasma Concentrations of Myeloid-Derived Growth Factor in Healthy

Dec 13, 2018 - ... the pathophysiology of MYDGF and its potential use as a biomarker or protein therapeutic in patients with acute MI or other disease...
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Plasma Concentrations of Myeloid-Derived Growth Factor in Healthy Individuals and Patients with Acute Myocardial Infarction as Assessed by Multiple Reaction Monitoring-Mass Spectrometry Felix Polten, Marc Reboll, Christian Widera, Tibor Kempf, Kerstin Bethmann, Priyanka Gupta, John Miglietta, A Pekcec, Jochen Tillmanns, Johann Bauersachs, Evangelos Giannitsis, Andreas Pich, and Kai C. Wollert Anal. Chem., Just Accepted Manuscript • DOI: 10.1021/acs.analchem.8b03041 • Publication Date (Web): 13 Dec 2018 Downloaded from http://pubs.acs.org on December 15, 2018

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is published by the American Chemical Society. 1155 Sixteenth Street N.W., Washington, DC 20036 Published by American Chemical Society. Copyright © American Chemical Society. However, no copyright claim is made to original U.S. Government works, or works produced by employees of any Commonwealth realm Crown government in the course of their duties.

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Figure 1 33 Page 29 of A

B S Y L Y F T Q F K ( lig h t)

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Figure 3 33 Page 31 of A

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M Y D G F  m e d ia n

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FOR TOC ONLY

Apparently healthy

Myocardial infarction Blood plasma In-gel digestion

SDS-PAGE

15 kDa

Internal standard

Triplicate MRM-MS

Peptide recovery

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