Polycyclic Hydrocarbons and Carcinogenesis

C a v a l i e r i , E r c o l e L., 289. Chang, Richard L., 63. Chiu, Pei-Lu, 19. Conney, A l l a n H., 63 ... J e r i n a , Donald M., 63. Kadlubar, ...
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Author Index

Amin, S h a n t u , 85 B e l a n d , F r e d e r i c k A., 341,371 C a v a l i e r i , E r c o l e L . , 289 Chang, R i c h a r d L . , 63 C h i u , P e i - L u , 19 Conney, A l l a n H., 63 D i p p l e , Anthony, 1 Dommen, J o s e f , 239 E i s e n s t a d t , E r i c , 327 F u , P e t e r P., 371 G e a c i n t o v , N i c h o l a s E . , 107 G l u s k e r , Jenny P., 125 H a r v e y , Ronald G., 35 H e c h t , S t e p h e n S., 85 H e f l i c h , R o b e r t H., 371 Hoffmann, D i e t r i c h , 85 Howard, P a u l C , 371 J e f f r e y , A l a n M., 185

J e r i n a , Donald M., 63 K a d l u b a r , F r e d F., 341 Kumar, Subodh, 63 L a V o i e , Edmond J . , 85 L e B r e t o n , P. R., 209 L e h r , Roland E . , 63 L e v i n , Wayne, 63 M a r n e t t , Lawrence J . , 307 M e l i k i a n , A s s i e h A., 85 M i l l e r , Kenneth J . , 239 Mushtaq., Mohammad, 19 Rogan, E l e a n o r G., 289 S a y e r , Jane M., 63 T a y l o r , E r i c R., 239 Wood, A l e x a n d e r W., 63 Y a g i , H a r u h i k o , 63 Yang, Shen K., 19

Subject Index

A

N-Acetoxy arylamides c a r c i n o g e n i c i t y , 347 e l e c t r o p h i l i c r e a c t i v i t y , 347 p r o p e r t i e s , 347 r e a c t i o n mechanism, 347-48 r o l e as u l t i m a t e c a r c i n o g e n s , 347 N-Acetoxy arylamines i s o l a t i o n , 350 m e t a b o l i c f o r m a t i o n , 350,352 r e a c t i o n mechanism, 350-52 r o l e as u l t i m a t e c a r c i n o g e n s , 352 A c t i v a t e d carcinogen-DNA i n t e r a c t i o n s , computer m o d e l i n g , 170,176 Activated carcinogen-nucleotide interactions d i s c u s s i o n , 159,161,169 r i b o s e 0 atom-methyl group i n t e r a c t i o n , 170,172f s t a c k i n g o f p o l y c y c l i c aromatic h y d r o c a r b o n s and b a s e s , 169-70,171f-72f

Activated carcinogen-polypeptide i n t e r a c t i o n s , 157 Aflatoxin B c r y s t a l s t r u c t u r e , 131 mode o f a c t i o n , 131 Alkylated nucleotides, s t r u c t u r e s , 161,165f-68f,169-70,173f Alkylated tripeptide, s t r u c t u r e , 157-59 A l k y l a t i o n o f amino g r o u p s o f DNA b a s e s , 139,140f Angstrom u n i t s , d e f i n i t i o n , 128 A n t h r a c e n e , c a r c i n o g e n i c a c t i v i t y , 45 A n t h r a c e n e d i h y d r o d i o l s , s y n t h e s i s , 45 A r y l n i t r o n e s , r e a c t i o n mechanism, 363f

B

Bay r e g i o n d e f i n i t i o n , 8,128 structures, 8 , l l f

397