Pressure-Dependent Retention and Selectivity in Reversed-Phase

Pressure-Dependent Retention and Selectivity in Reversed-Phase ...https://pubs.acs.org/doi/10.1021/ac960818wDepartment of Chemistry, University of Mic...
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Anal. Chem. 1997, 69, 643-649

Pressure-Dependent Retention and Selectivity in Reversed-Phase Liquid Chromatographic Separations Using β-Cyclodextrin Stationary Phases Moira C. Ringo and Christine E. Evans*

Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109-1055

The influence of pressure on solute retention in liquid chromatography is commonly ignored due to the small compressibility of polar mobile phases. However, the equilibrium processes driving solute retention may be significantly affected by pressure, even under the modest conditions commonly encountered in HPLC (