Protein Purification - American Chemical Society

separation, site-specific proteolysis of fusion proteins, and the use of applied electric fields for downstream processing. Michael R. Ladisch, Editor...
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MEETINGS

Protein Purification From Molecular Mechanisms to Large-Scale Processes

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his timely new volume gives real exam­ ples of how separation techniques are used in industry with recombinant pro­ teins, and emphasizes which techniques might be more useful than others in real world applications. With contributions from leading experts in the field, this volume covers both academic and industrial interests. It shows how series can be applied to developing strategies and emphasizes appropriate approaches for diffi­ cult protein separation problems. New separation techniques are evaluated for their practicality in connection with recom­ binant proteins on an industrial scale. These include: • adsorption

• extraction • liquid chromatography • centrifugation • electrophoresis Some of the specific topics discussed are adsorptive separations, mechanisms of protein retention in hydrophobic interaction chroma­ tography, radial-flow affinity chromatography for trypsin purification, metal-affinity protein separation, site-specific proteolysis of fusion proteins, and the use of applied electric fields for downstream processing. Michael R. Ladisch, Editor. Purdue University Richard C. Willson, Editor. University of Houston Chih-duen C. Painton, Editor. Mallinckrodt Medical. Inc. Stuart E. Builder, Editor, Genetech, Inc. Developed from a symposium sponsored by the Division of Biochemical Technology of the American Chemical Society ACS Symposium Series No. 4 2 7 280 pages (1990) Clothbound ISBN 0-8412-1790-4 LC 90-35551

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Short Courses and Workshops • Workshop on Field-Flow Frac­ tionation. Feb. 2. Salt Lake City, UT. Contact: Julie Westwood, FFF Re­ search Center, Dept. of Chemistry, University of Utah, Salt Lake City, UT 84112 (801-581-5419) • Quality Assurance in Analytical Laboratories. Feb. 4-5. Tallahassee, FL. Contact: Gail Parker, Florida Dept. of Agriculture, 3125 Conner Blvd., Tallahassee, FL 32399 • Capillary Electrophoresis, Micro LC, and MS Analysis of Proteins and Peptides. March 26-27. Lincoln, NE. Contact: Joseph Tehrani, Isco, P.O. Box 5347, Lincoln, NE 68505 (402-4640231) • Managing Drug Testing in the Workplace. April 10. San Diego, CA. Contact: Ruth Mclntyre-Birkner, MBA, Inc., 5865 Dovetail Dr., Agoura Hills, CA 91301 (818-707-2583) • Materials Analysis for Problem Solving, QA/QC, and Process Char­ acterization in Industry. April 17 and July 17. Sunnyvale, CA. Contact: Carlo Delumpa, Surface Science Lab­ oratories, 1206 Charleston Rd., Moun­ tain View, CA 94043

70 A · ANALYTICAL CHEMISTRY, VOL. 63, NO. 2, JANUARY 15, 1991

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