Books In conclusion, I highly recommend this work as a quantitative analysis text. Carbon-13 Nuclear Magnetic Resonance Spectroscopy. 2nd éd. G. C. Levy, R. L. Lichter, G. L. Nelson, xiv + 338 pages. John Wiley & Sons, 605 Third Ave., New York, N.Y. 10016. 1980. $22.50
Reviewed by Robert G. Bryant, Department of Chemistry, University of Minnesota, Minneapolis, Minn. 55455 The authors' stated intentions are to provide an introduction to 13C NMR spectroscopy for organic chemists, to review an expanding number of techniques that may provide useful structural or dynamic information, and to summarize a large body of experimental spectroscopic data. The magnitude of the task is so great that a single volume of 328 pages cannot address all aspects with equal clarity. The text begins with a brief introduction to the NMR experiment itself, and mentions briefly the several different techniques that are amplified in
later chapters. The second chapter addresses problems and spectral characteristics that are unique to carbon, as opposed to protons, and points out some critical interpretative traps for the uninformed. Chapters 3 and 4 are devoted to discussions of aliphatic and aromatic compounds, respectively, while chapter 5 deals with the rest of the organic functional groups. Chapter 6 is devoted to ions, radicals, and metal complexes. Separate chapters deal with polymers, relaxation studies, biomolecules, and special techniques. The language of the book is informal. In my opinion it would be very difficult to use this book as the only introduction to NMR. However, the authors do provide several problems, scattered throughout the text, which give the reader an opportunity to test comprehension. The book does a good job of supplying references to the original literature at the end of each chapter so that the reader may easily find more extensive treatments when the need arises. The strength of the book is not that it provides lucid presentations of all interesting aspects of carbon NMR spectroscopy, but that it
drug identification atlas
Agriculture Canada's " Drug Identification Atlas" is available to the public at a price of $300 (Canadian). Contained in three 13/4" seven-ring binders, the Atlas provides the detailed protocols
Agriculture Canada
supplies a well-organized collection of data such as chemical shifts, coupling constants, substituent effects, relaxation rates, and Overhauser effects. This book should be a very useful reference for the practicing organic chemist who takes advantage of carbon NMR data in drawing structural and dynamic conclusions.
Medical and Biological Applications of Electrochemical Devices. Jiri Koryta, Ed. ix + 331 pages. John Wiley & Sons, Inc., 605 Third Ave., New York, N.Y. 10016. 1980. $79
Reviewed by Jiri Janata, Department of Bioengineering, University of Utah, Salt Lake City, Utah 84112 Electroanalytical sensors are especially appealing for biomedical applications for a variety of reasons: They can be readily adopted to continuous mode of measurement both in vivo and in vitro, electrodes can be made very small (~1 μ) and the signal can be, in some cases, related to the activi ty rather than to concentration of
Each pure drug was subjected to five different analytical methods under the same protocols at three separate and independent laborato ries. The results were collated and are pre sented in chart and tabular form in the Atlas. The analytical methods used were: 1. Gas liquid chromatography 2. Thin layer chromatography 3. Infrared spectrophotometry 4. Ultraviolet spectrophotometry 5. Mass spectrometry An additional 250 drugs are currently being analyzed under the same protocols and will be available for a fee in approximately 2 years. Atlas data can be duplicated by any expe rienced forensic chemist following exactly the protocols provided. Only prepaid orders will be accepted (Certified cheque or money order in Canadian funds made out to the Receiver General of Canada). Additional information, including drug index, may be obtained by writing to: The Director Race Track Division Agriculture Canada 930 Carling Avenue Ottawa, Ontario CANADA K1A0C5
Canada ANALYTICAL CHEMISTRY, VOL. 53, NO. 4, APRIL 1981 · 611 A
