Rational Drug Design - ACS Publications - American Chemical Society

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Downloaded by UNIV OF NEBRASKA - LINCOLN on December 30, 2014 | http://pubs.acs.org Publication Date: July 7, 1999 | doi: 10.1021/bk-1999-0719.fw001

Rational Drug Design

In Rational Drug Design; Parrill, A., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1999.

In Rational Drug Design; Parrill, A., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1999.

Downloaded by UNIV OF NEBRASKA - LINCOLN on December 30, 2014 | http://pubs.acs.org Publication Date: July 7, 1999 | doi: 10.1021/bk-1999-0719.fw001

Downloaded by UNIV OF NEBRASKA - LINCOLN on December 30, 2014 | http://pubs.acs.org Publication Date: July 7, 1999 | doi: 10.1021/bk-1999-0719.fw001

ACS

SYMPOSIUM SERIES

Rational Drug Design Novel Methodology and Practical Applications

Abby L. Parrill, EDITOR University of Memphis

M. Rami Reddy, EDITOR Metabasis Therapeutics, Inc.

American Chemical Society

In Rational Drug Design; Parrill, A., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1999.

719

RS 420 .R37 1999 c . 1

R a t i o n a l drug design : novel methodology and p r a c t i c a l

Libraryof Congress Cataloging-in-Publication Data

Downloaded by UNIV OF NEBRASKA - LINCOLN on December 30, 2014 | http://pubs.acs.org Publication Date: July 7, 1999 | doi: 10.1021/bk-1999-0719.fw001

Rational drug design : novel methodology and practical applications / Abby L. Parrill, M. Rami Reddy, editors. p.

cm. -- (ACS symposium series ; 719)

"Developed from a symposium sponsored by the Division of Computers in Chemistry at the 214 National Meeting of the American Chemical Society, Las Vegas, Nevada, September 7-12, 1997." th

Includes bibliographical references and index. ISBN 0-8412-3603-8 1. Drugs-Design--Congresses. 2. Drugs-Structure-activity relationships--Congresses. 3. Combinatorial chemistry--Congresses. I. Parrill, Abby L. II. Rami Reddy, M., 1934-. III. American Chemical Society. Division of Computers in Chemistry. IV. American Chemical Society. Meeting (214 : 1997 : Las Vegas, Nev.) V. Series. th

RS420.R37 1999 615'.19--dc21

98-32087 CIP

The paper used in this publication meets the minimum reqirements of the American National Standard for Information Sciences—Permanence of Paper for Printed Library Materials, ANSI Z39.481984. Copyright © 1999 American Chemical Society Distributed by Oxford University Press All Rights Reserved. Reprographic copying beyond that permitted by Sections 107 or 108 of the U.S. Copyright Act is allowed for internal use only, provided that a per-chapter fee of $20.00 plus $0.50 per page is paid to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, USA. Republication or reproduction for sale of pages in this book is permitted only under license from ACS. Direct these and other permissions requests to ACS Copyright Office, Publications Division, 1155 16th Street, N.W., Washington, DC 20036. The citation of trade names and/or names of manufacturers in this publication is not to be construed as an endorsement or as approval by ACS of the commercial products or services referenced herein; nor should the mere reference herein to any drawing, specification, chemical process, or other data be regarded as a license or as a conveyance of any right or permission to the holder, reader, or any other person or corporation, to manufacture, reproduce, use, or sell any patented invention or copyrighted work that may in any way be related thereto. Registered names, trademarks, etc., used in this publication, even without specific indication thereof, are not to be considered unprotected by law. PRINTED IN THE UNITED STATES OF AMERICA

In Rational Drug Design; Parrill, A., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1999.

Advisory Board Downloaded by UNIV OF NEBRASKA - LINCOLN on December 30, 2014 | http://pubs.acs.org Publication Date: July 7, 1999 | doi: 10.1021/bk-1999-0719.fw001

A C S Symposium Series

M a r y E. C a s t e l l i o n ChemEdit Company

Omkaram Nalamasu AT&T Bell Laboratories

A r t h u r B. Ellis University of Wisconsin at Madison

K i n a m Park Purdue University

Jeffrey S. Gaffney Argonne National Laboratory

Katherine R . Porter Duke University

G u n d a I. G e o r g University of Kansas

D o u g l a s A. S m i t h

Lawrence P. Klemann Nabisco Foods Group R i c h a r d N. L o e p p k y University of Missouri C y n t h i a A. M a r y a n o f f R. W. Johnson Pharmaceutical Research Institute R o g e r A. M i n e a r University of Illinois at Urbana-Champaign

The DAS Group, Inc. M a r t i n R . Tant Eastman Chemical Co. M i c h a e l D. T a y l o r Parke-Davis Pharmaceutical Research Leroy Β . Townsend University of Michigan William C . W a l k e r DuPont Company

In Rational Drug Design; Parrill, A., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1999.

Downloaded by UNIV OF NEBRASKA - LINCOLN on December 30, 2014 | http://pubs.acs.org Publication Date: July 7, 1999 | doi: 10.1021/bk-1999-0719.fw001

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In Rational Drug Design; Parrill, A., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1999.