Serving the chemical, life sciences, and laboratory worlds
VOLUME 92, NUMBER 40 OCTOBER 6, 2014
COVER STORY
READY TO TAKE ON CANCER Reprogrammed T cells give amazing results in blood cancer trials; firms race to commercialize the approach. PAGE 12
QUOTE OF THE WEEK “In chemistry, the grapevine is pretty small.”
NEWS OF THE WEEK 7
Prime minister is seen as a leader who can bridge disputes, such as those involving pharmaceuticals. 8
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GOVERNMENT & POLICY
APTAMERS TAG SMALL MOLECULES
Folded oligonucleotides recognize complexes of receptors bound to sugars and amino acids. 9
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9
30
Agency ignores many hazardous chemicals dumped into sewage waste streams, OIG says.
56 10
SCIENCE & TECHNOLOGY
ARTIFICIAL SWEETENERS
Intense competition from China is putting Western manufacturers on the ropes. BENZOXAZINOID BACK AT YOU
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Turnabout is fair play when the fall armyworm unmasks and returns a plant toxin to its host. 11
STREAMLINING DRUG DISCOVERY
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NATIONAL CHEMISTRY WEEK
THE DEPARTMENTS 3 4 44 47
CONCENTRATES
PROTECTING FROZEN CELLS
Scientists seek cryoprotectant molecules that prevent ice from damaging frozen cells, such as stored blood.
Festivities celebrate “The Sweet Side of Chemistry—Candy.”
BUSINESS
CONCENTRATES FROM THE SCENES PUBLISHING IN PARALLEL
Chemists discuss deals struck with colleagues publishing similar papers around the same time.
Method identifies microbes able to produce specific natural product families, researchers say. 11
EXPORT AGENCY ON THE EDGE
Chemical industry fights to save government lender that helps boost overseas sales.
CALL FOR MORE EPA ACTION
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CONCENTRATES STRATEGY FOR SQUISHING SUPERBUGS
White House and PCAST direct their attention toward combating antibiotic resistance.
BOOSTING ETHANOL YIELDS
Tweaking yeasts to tolerate higher temperatures and alcohol levels improves their productivity.
ANALYTICAL INSTRUMENTS ENTER CHINA
Trade show Analytica China reveals domestic and foreign manufacturers are selling in the country.
Manufacturers threaten litigation over pending FDA rule on warning label changes. 8
RENEWABLE REPLACEMENTS
Fungus-based-material firms see success as they compete with the packaging and wood industries.
GENERICS MAKERS PUT UP A FIGHT
RICHARD A. LERNER, BIOCHEMIST, SCRIPPS RESEARCH INSTITUTE CALIFORNIA PAGE 39
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INDIA’S MODI WOWS THE U.S.
EDITOR’S PAGE LETTERS ACS NEWS AWARDS
COVER: Richard C. Smith CENEAR 92 (40 ) 1–56 • ISSN 0 00 9-2347
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OBITUARIES ACS CAREER TIPS CLASSIFIEDS NEWSCRIPTS
