Remarkable Electronic and Steric Effects in the Nitrile

Sep 14, 2007 - Remarkable Electronic and Steric Effects in the Nitrile Biotransformations for the Preparation of Enantiopure Functionalized Carboxylic...
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Vol. 72, 2007 Ming Gao, De-Xian Wang, Qi-Yu Zheng, Zhi-Tang Huang, and Mei-Xiang Wang*. Remarkable Electronic and Steric Effects in the Nitrile Biotransformations for the Preparation of Enantiopure Functionalized Carboxylic Acids and Amides: Implication for an Unsaturated Carbon-Carbon Bond Binding Domain of the Amidase.

Page 6064. The absolute configurations of products 12-15 in Scheme 2 were drawn incorrectly. The correct structures are shown below. SCHEME 2.

Synthesis of Enantiopure γ-Lactams

JO701889V 10.1021/jo701889v Published on Web 09/14/2007

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J. Org. Chem. 2007, 72, 8152