t i m e m o n i t o r t h e performance of t h e spectrometer system. Information gleaned from t h e b a c k g r o u n d emission could be used to notify t h e operator of changes in t h e solvent, s a m p l e m a t r i x , nebulizer efficiency, or p l a s m a t e m perature. F u t u r e applications of C T D s will arise as scientists ask more complex a n d detailed questions a b o u t physical systems. Researchers often are con s t r a i n e d by i n s t r u m e n t a l limitations of sensitivity or t i m e t o measuring only a few p a r a m e t e r s of a physical system. A sensitive m u l t i c h a n n e l C T D detector, coupled with t h e right optical a n d com p u t e r s y s t e m s , r e l a x e s t h e s e con s t r a i n t s a n d allows scientists t o m e a sure several p a r a m e t e r s s i m u l t a n e o u s ly. T h e b r o a d objective of research on C T D systems is to develop i n s t r u m e n t a t i o n t h a t does n o t limit a scientist's ability to g a t h e r all of t h e spectral, spa tial, a n d t e m p o r a l d a t a of a physical system. We thank Jeanne Pemberton and Ray Sobocinski of the Department of Chemistry, University of Arizona, for sharing their work comparing the sen sitivity of PMTs and CCDs in Raman spectrosco py. We also thank Neal Armstrong of the Depart ment of Chemistry, University of Arizona, for the metal-phthalocyanine thin-film samples. We ac knowledge Richard Aikens and William McCurnin of Photometries Ltd. (Tucson, Ariz.) for many use ful discussions on the design and application of scientific CTD cameras.
This article is based on work partially funded by the Office of Naval Research and SmithKline Beckman.
References (1) Kristian, J.; Blouke, M. Sci. Am. 1982, 247, 67-74. (2) Sweedler, J. V.; Bilhorn, R. B.; Epper son, P. M.; Sims, G. R.; Denton, M. B. Anal. Chem. 1988, 60(4), 282 A-291 A. (3) Hafemeister D.; Romm, J. J.; Tsipis, K. Sci. Am. 1985,252, 39-45. (4) Hiraoka, Y.; Sedat, J. W.; Agard, D. A. Science 1987,238, 36-41. (5) Kinney, J. H.; Johnson, Q. C ; Bonse, U.; Nusshardt, R.; Nichols, M. C. Proc. SPIE 1986, 691, 43-50. (6) Harris, S. E.; Squires, R. H.; Bergeron, Ε. Μ. In Oceans '87; Marine Technical Society and IEEE: Nova Scotia, 1987. (7) Naday, I.; Strauss, M. G.; Sherman, I. S.; Kraimer, M. R.; Westbrook, E. M. Opt. Eng. 1987,26, 788-94. (8) Aikens, R. S.; Lynds, C. R.; Nelson, R. E. Proc. SPIE 1976, 78, 65-72. (9) Burke, H. K.; Brown, D. M.; Grafinger, Α.; Michon, G. J.; Tomlinson, H. W.; Vogelsong, T. L.; Wilson, R. Proc. SPIE 1979 203 124-9 (10) Ratzlaïf, K. L.; Paul, S. L. Appl. Spectrosc. 1979, 33, 240-5. (11) Oke, J. B. Proc. SPIE 1981,290,45-50. (12) Goad, L. E. Proc. SPIE 1982, 331,1306. (13) York, D. G.; Jenkins, Ε. Β.; Zucchino, P.; Lowrance, J. L.; Long, D.; Songaila, A. Proc. SPIE 1981,290, 202-7. (14) Roesler, F. L.; Scherb, F.; Oliversen, K.; Jaehnig, K.; Williams, T.; York, D. G.; Jenkins, Ε. Β. Proc. SPIE 1981, 290, 1805.
(15) Epperson, P. M.; Jalkian, R. D.; Den ton, M. B., unpublished results. (16) Richardson, J. H.; Ando, M. E. Anal. Chem. 1977,49, 955-9. (17) Murray, C. Α.; Dierker, S. B. J. Opt. Soc. Am. A 1986, 3, 2151-59. (18) Pemberton, J.; Sobocinski, R.; Univer sity of Arizona, unpublished results. (19) Denton, M. B.; Lewis, Η. Α.; Sims, G. R. In Multichannel Image Detectors Vol. 2; Talmi, Y., Ed.; ACS Symposium Series 236; American Chemical Society: Wash ington, D.C., 1983; 133-54. (20) Aikens, R. S.; Epperson, P. M.; Den ton, M. B. Proc. SPIE 1984, 501, 49-54. (21) Epperson, P. M.; Denton, M. B.; Ai kens, R. S. Abstracts of Papers, 1986 Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, La.; American Chemical So ciety: Washington, D. C , 1986; Abstract 520. (22) Bilhorn, R. B.; Epperson, P. M.; Sweedler, J. V.; Denton, M. B. Appl. Spectrosc. 1987, 41, 1125-36. (23) Epperson, P. M.; Sims, T. M.; Sims, G. R.; Denton, M. B., unpublished results. (24) Klofta, T. J.; Rieke, P. C ; Linkous, C. Α.; Buttner, W. J.; Nanthakumar, Α.; Mewborn, T. D.; Armstrong, N. R. J. Electrochem. Soc. 1985,132, 2134-44. (25) Sims, G. R.; Denton, Μ. Β. In Multi channel Image Detectors; Talmi, Y., Ed.; ACS Symposium Series 236; American Chemical Society: Washington, D. C , 1983; pp. 117-32. (26) Bilhorn, R. B.; Ph.D. Dissertation, University of Arizona, August 1987. (27) Keliher, P. N.; Wohlers, C. C. Anal. Chem. 1976, 48, 333 A-340 A. (28) Photometries Ltd. literature, Photometrics Ltd., Tucson, Ariz. 85745 (29) Denton, M. B. Analvst 1987.112, 34753.
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ANALYTICAL CHEMISTRY, VOL. 60, NO. 5, MARCH 1, 1988 · 335 A
