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Commemorative envelopes (above) featuring the first ACS president and St. Louis meeting site were sold at exposition with on-site special cancellation...
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MEETINGS

14th ACS Northeast Regional Meeting The 14th ACS Northeast Regional Meeting will be held June 10-14 on the campus of Fairfield University, Fairfield, Conn. The Western Connecticut and New Haven sections will host the meeting. The general chairman is Donald L. Swanson, American Cyanamid Co., Stamford, Conn. The technical program features invited and contributed papers in 11 symposia. In addition there will be general contributed papers in the several fields of chemistry listed below. Two ACS Short Courses are scheduled in conjunction with the meeting; "Chemical Engineering for Chemists" will be presented Wednesday through Friday, and "Monitoring and Troubleshooting Chromatographic Systems" is planned on Wednesday and Thursday. For additional information about these courses contact ACS Short Courses, 1155—16th St., N.W., Washington, D.C. 20036; telephone (202) 872-4508. All participants are invited to attend an ice-breaker reception on Sunday from 5 to 7 PM. The general mixer will be in the gymnasium from 5 to 7 PM on Monday. Women chemists will have a Dutch-treat luncheon at 12:30 PM on Tuesday. A chemical exposition will be held Monday through Wednesday in the gymnasium. The NERM banquet will be on Monday evening from 7 to 9 in the Campus Center. Ray R. Irani of Occidental Chemicals Co. will deliver the address, "The Chemical Industry in the 80s—Hurdles and Opportunities." The Northeast Regional Award for Excellence in High School Chemistry Teaching will Special Events SUNDAY 5:00-8:00 PM—Registration, Gymnasium 5:00-7:00 PM—Ice Breaker, Campus Center

MONDAY 8:00 AM-5:00 PM—Registration, Gymnasium 9:00 AM-5:00 PM—ACS Employment Clearing House 10:00 AM-7:00 PM—Chemical Exposition, Gymnasium 4:00 PM-5:30 PM—Meeting of Councilors am* I nca1

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TUESDAY 8:00 AM-5:00 PM—Registration, Gymnasium 9:00 AM-5:30 PM—Cooperative Education Workshop, Bannow Hall, Room 137 9:00 AM-5:00 PM—ACS Employment Clearing House 10:00 AM-6:00 PM—Chemical Exposition, Gymnasium

April 23, 1984 C&EN

WEDNESDAY 8:00 AM-Noon—Registration, Gymnasium 8:30 AM-5:00 PM—Short Course, on Monitoring and Troubleshooting Chromatographic Systems, Bannow Hall, Room

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Bannow Han 5:00 PM-7:00 PM—Mixer, Gymnasium 7:00 PM-9:00 PM—Banquet, Campus Center "The Chemical Industry in the 80s—Hurdles and Opportunities." R. R. Irani. Ticket or Campus Meal Plan Required. ACS Northeast Regional Award for High School Chemistry Teaching

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10:00 AM-2.00 PM—Poster Session, Gymnasium 12:30-2:00 PM—Luncheon for Women Chemists, Campus Center 5:00 PM-6:30 PM—Chemical Education Social Hour 5:15 PM-6:15 PM—Chemical Education Buffet 7:00 PM-10:30 PM—Chemical Education Towards the 21st Century. Prof. J. Bell, Keynote Speaker

9:00 AM-5-.30 PM—Short Course, on Chemical Engineering for Chemists, Bannow Hall, Room 131 10:00 AM-2:00 PM—Chemical Exposition, Gymnasium 12:30 PM—NERM Steering Committee, Campus Center Faculty Meeting Room

be presented. For registrants residing in the Fairfield dormitories on Monday night, the banquet is included in the meal plan. Others should purchase tickets ($12) on the advance form (page 47). A special Cooperative Education Workshop will be offered on Tuesday from 9 AM to 5:30 PM; for more information contact Paul Hines; telephone (203) 797-4284. A chemical education social hour and buffet will follow. The symposium, "Chemical Education Towards the 21st Century" will begin with a keynote address by Jerry A. Bell of Simmons College. An ACS National Employment Clearing House will be held during the meeting. Candidates and employers should contact the Employment Aids Office, 1155—16th St., N.W., Washington, D.C, telephone (202) 872-4528 for forms and additional information. Participants are encouraged to preregister by completing the form on page 47. Registration materials will be available in the gymnasium during the meeting. Housing is available on the Fairfield University campus, and room rates include meals. Please use the form on page 47 to request more information about campus housing and food service. A list of area hotels/motels is given on page 47. For additional meeting information contact the general chairman or the vice-chairman, John Domijan, Box 109, Quinnipiac College, Hamden, Conn. 06518; telephone (203) 288-5251, Ext 275. Symposium on Applications of Molecular Orbital Theory TUESDAY MORNING & AFTERNOON Bannow Hall, Room 254 K. B.Wiberg, Presiding 9:00—1. Ab-initio Calculations on MediumSized Molecules. J. M. Schulman, R. L. Disch 10:00—2. Electronic Structure of Transition Metal Systems. M. D. Newton 11:00—3. Theoretical Thermochemistry. J. A. Pople 2:00—4. Atomization of Molecular Orbitals. L. Z. kVteft 3:00—5. Transition Structures for Electrophilic Additions and Cycloadditions. K. N. Houk, N. G. Rondan 4:00—6. Electrophilic Cleavage of Small Ring Compounds. K. B. Wiberg

THURSDAY

Chemical Education

8:30 AM-5:00 PM—Monitoring and Troubleshooting Chromatographic Systems (continued), Bannow Hall, Room 253 9:00 AM-5:30 PM—Chemical Engineering for Chemists (continued), Bannow Hall, Room 131

TUESDAY

FRIDAY

{Supported by Clairot)

9:00 AM-5:30 PM—Chemical Engineering for Chemists (continued), Bannow Hall, Room 131

7:15—7. Teacher, Teacher, Teacher! J. A. Bell

EVENING

Campus Center, Oak Room Symposium on Chemical Education Towards the 21st Century R. Festa, Presiding

8:05—8. Computers: a Unique Catalyst for the Learning Process. P. A. Cauchon 8:35—9. Teaching and Learning Between the Input Valve and Output Spigot—an Ecological View. E. Meyer, R. Festa 9:05—10. Continuing Education and Curriculum Development. E. M. North, R. Festa 9:35—11. Educating for Scientific Literacy. E. S. Lipeles

WEDNESDAY MORNING Bannow Hall, Room 138 General Session B. George, Presiding 9:00—12. Why Do Students Choose Chemistry as a Major? B. George, V. P. Wystrach, f.. r©r*\r.s 9:30—13. Developing Professionalism of Students in Chemistry. D. Drum 10:00—14. Older Scientists—Retraining for the 21st Century. E. S. Weaver 10:30—15. Teaching Undergraduates About On-Line Information Retrieval. A. W. Kozlowski 11:00—16. Introduction to Industrial Chemistry—a Proposed Undergraduate Course. H. L. White 11:30—17. Polymer Chemistry in the General Chemistry Course. D. A. Williams 12:00—18. Mixing Biochemistry into the Teaching of Organic Chemistry. H. C Van Woert Jr.

Symposium on Chemical Separations and Identifications TUESDAY MORNING & AFTERNOON Campus Center, Oak Room

W. A. Nichols, Presiding 9:00—19. Applications of a Cold-on-Column Capillary Injector Emphasizing Resolution and Speed. J. W. Frank 10:00—20. New Low-Volume Single Filament—Single-Column Thermal Conductivity Detector for Use with Open Tubular Columns. R. C. Gearhart, R. R. Freeman 11:00—21. Role of Gamma Radiation in the Preparation of Fused Silica Capillary Columns. J. A. Hubball, P. Dimauro, E. Barry 2:00—22. Identification of Unknown Samples by Gas Chromatography Utilizing Detectors in Series. A Wllshire, J. N. Driscoll, E. S. Atwood, P. Ferioli, D. Conron 3:00—23. New Applications of High-Performance Gel Permeation Chromatography. K. Alden 4:00—24. Application of Ion Chromatography. J. Stillian

Chemical Technicians Symposium MONDAY MORNING & AFTERNOON Bannow Hall, Room 135

R. Pick well, Presiding 9:00—Introductory Remarks. B. Jacobs 9:10—Keynote Address: Continuing Your Education. W. F. Murphy 9:35—25. Chemical Technician: Profession or Stepping-Stone? R. J. Pickwell 10:00—26. Development of Flame-Ftetardant Medical Pads for the Boston Fire Department. B. Williams 10:25—Intermission 10:45—27. Personnel Monitoring Method for the Determination of Nonaroclor Chlorinated Biphenyls. C. Lonardo, P. E. Kaufmann 11:10—28. Synthesis of Heterocyclic Nitriles via Isocyanate Dehydration of Oximes. L. Welch, R. J. Chriss 11:30—29. Matrix Interference Negation for Serum Calcium Determination by AA: Standard Addition and Calibration Curve Methods. K. Claffey, R. J. Merrer 1:55—30. Ion-Selective Electrode Measurement of Some Surfactant Properties. M. Berthiaume, R. Oteri 2:20—31. Some Fundamental Characteristics of Black Hair. J. Epps 2:45—32. State of the Art of Chemical Libraries. T. Reardon 3:10—Intermission 3:25—33. Introduction to Fourier Transform Infrared Spectroscopy. M. Sabo 3:50—34. Influence of Formulation on the Physical Properties of Cured RTV Silicone Sealants. E. Pohl, P. Morabito 4:15—Closing Remarks. B. Jacobs

Computers in Chemistry

10:30—38. Computer-Assisted Instruction, in Chemistry, at Fairfield University. F. Llsman

TUESDAY MORNING & AFTERNOON Bannow Hall, Room 253 Symposium on Computers in Chemistry D. Relyea, Presiding (Supported by Uniroyal Chemical) 9:00—39. Microcomputer-Aided Instruction in Physical Chemistry. B. Joshi 10:00—40. Drug Information System of the National Cancer Institute. G. Milne 11:00—41. Computer Implementation of Systematic Synthesis Design. J. Hendrickson 2:00—42. Computers in Infrared Spectroscopy. R Hannah 3:00—43. Intramolecular Potentials from Computational Models of Observed Crystal Structures. W. Busing 4:00—44. Computer-Assisted Studies of Structure-Activity Relations. E. WhalenPedersen, P. Jurs —45. Withdrawn

Hazardous Waste Management TUESDAY MORNING & AFTERNOON School of Nursing, Room 214 General Session

A. Pulito, Presiding 9:00—46. National Human Monitoring Program: an Overview. J. Breen, J. Remmers.S. Strassman-Sundy, F. Kutz 9:25—47. ICAO/EPA Compliance Testing. N. Campbell, M. Williams, R. Groth 9:50—48. Controlling Friable AsbestosContaining Materials in Buildings. J. Breen, C. Stroup, D. Mayer, D. Keyes, B. Price 10:15—49. Remote Laser Fluorescence Analysis of Groundwater Contaminants. W. Chudyk, J. Kenny 10:40—50. Adsorption of Inorganic Tin and Methylated Tin Compounds Under Simulated Estuarine Conditions. O. Donard, J. Weber 11:05—51. Detection of Polychlorinated Dibenzofuranes (PCDFs) in PCB-Transformer Fluids. L. Verbit, A. Pahng, R. Margolin 2:00—52. Environmental Implications of Methylation of Lead(ll) and Methyllead(V) Ions by a Methylcobalt(lll) Macrocycle Donor. S. Rapsomanlkis, J. Weber 2:25—53. Competitive Sorption of Nitrophenols and 2,6-Dimethylphenol by a Lake Sediment. P. Isaacson, C. Frink 2:50—54. Translocation and Metabolism of 3,4,3',4'-Tetrachloroazobenzene in Soybean Plants. B. Worobey 3:15—55. Recovery and Reuse of Waste Organic Solvents in Biomedical Research Institutions. L. Gibbs 3:40—56. Disposal of Organic Chemical Liquid Wastes. D. Drum 4:05—57. Kinetics and Products of Hydrolysis of 1,2-Dibromo-3-Chloropropane. N. Burlinson, L. Lee, D. Rosenblatt 4:30—58. Hazardous Waste Incineration Parameters. B. Pierson, D. Drum

MONDAY MORNING

D. Relyea, Presiding

WEDNESDAY MORNING & AFTERNOON Gonzaga Hall Symposium on Hazardous Waste Management P. Duff, Presiding 9:00—59. Integrated Hazardous Waste Management. M. Overcash 10:00—60. Hazardous Waste Management in Europe. H. Fabian, H. Fuhr 11:00—61. Recent Advances in Secure Landfill Technology. R. Mutch Jr., M. Brother

TUESDAY AFTERNOON School of Nursing, Room 203-205 General Session

H. Hess, Presiding

2:00—81. Cannabinoid Receptor Site Models. L. Melvin, M. Johnson, G. Milne 2:20—82. Correlation Between the Reverse-Phase Chromatographic Retention Times and Kinetic Binding Characteristics of Dihydropyridine Calcium Channel Inhibitors. G. Krol, A. Noe 2:40—83. Radiodinated 1-Aminoalkylcarbonyl Derivatives of 4-Phenyl Piperazine as PoMedicinal Chemistry tential Brain Imaging Agents. T. El-Shourbagy, R. Hanson 3:00—84. Synthesis and Evaluation of RaMONDAY MORNING diolabeled Phenyl Piperazine Derivatives for Mycardial Imaging. M. Hassan, R. Gonzaga Hall Hanson Symposium on Medicinal Chemistry 3:20—85. Use of a Novel Oxazole Rearrangement for the Synthesis of Antiulcer M. Tishler, Presiding Drugs. J. LaMattina, C. Mularski {Supported by Pfizer, Miles Laboratories, ACS 3:40—86. Synthesis and Antitumor Activity Division of Medicinal Chemistry) of Bicyclic and Tricyclic Anthramycin An9:00—65. Human Interferons: from the Past alogs. T. Kaneko, H. Wong, T. Doyle, W. and into the Future. S. Pestka Bradner, W. Rose 9:45—66. X-Ray Crystallography and Drug 4:00—87. Facile Conversion of Hantzsch Design. M. N. G. James Type 4-Aryl-1,4-Dihydropyridines into 210:30—67. Brain Catecholamine Receptors. Methyl - 4-Aryl-5-Oxo - 5,7-DihydrofuroP. Seeman [3,4-b]Pyridine-3-Carboxylates. J. Young 11:15—68. New Directions and Opportunities 4:20—88. Synthetic Route to Phosphonate for the Chemist in the Pharmaceutical InAnalogs of 5-Phosphorylribose 1-«-Didustry. R. Hirschmann phosphate. R. McClurd 4:40—88a. Short and Efficient Synthesis of (2S,3R)-Oxido-5-c/s-Undecen-1-al, a Total Synthesis of LTB4. Y. Yee MONDAY

AFTERNOON

Gonzaga Hall General Session K. Freter, Presiding 2:00—69. Mechanism of Inhibition of /3-Lactamases by Certain Cephalosporins. W. Faraci, R. Pratt 2:20—70. Steric and Electronic Aspects of Recognition of Penicillins and 7,7-Dichloro-4«-Carboxy-2-Thiabicyclo [3.1.0] Heptan-6-One by Penicillinase, D,D-Carboxypeptidase, and D,D-Carboxypeptidase-Transpeptidase. B. Tomczuk, G. HHe, A. Kumar 2:40—71. 6 and 6,6-Disubstituted Penems. M. Menard 3:00—72. Synthesis and Antibacterial Activity of 2-Methoxycarbonylmethylene Cephalosporins. C. Kim, P. Misco, U. Haynes, D. McGregor 3:20—73. Synthesis and Antibacterial Activity of Indolmycin Analogs. J. Dirlam, S. Hecker, D. Clark, N. Elliott, W. Windisch, A. Girard, M. Fritz 3:40—74. Design and Synthesis of Potent Renin Inhibitors. M. Bock 4:00—75. Synthesis and Complement Inhibitory Activities of 4-(2-Phenyl-1H-lndol-3-1) Cyclohexane-1-carboxylic Acids. D. Bailey, R. Johnson, G. DeGrazia, E. Alexander, R. Powles, R. Patrick, B. Heerdt, M. Fairbain, D. Pruden 4:20—76. Nontricyclic Antidepressant Agents Derived from cis- and frans-1-Amino-4aryltetralins. W. Welch, A. Kraska, R. Sarges, B. Koe 4:40—76A. Computer-Generated Model of Urokinase. A. Fliri, B. Dominy

Symposium on Organometallic Chemistry MONDAY MORNING & AFTERNOON Bannow Hall, Room 254 R. Schrock,

Presiding

(Supported by Stauffer Chemical) 9:00—89. Cationic Alkylidene Complexes of Tungsten. N. Cooper, J. Hayes, G. Miller, P. Jernakoff 10:00—90. Organometallic Chemistry of Fe4C Clusters. J. Bradley, S. Harris 11:00—91. Synthesis and Catalysis by Complexes Containing a Metal-Carbon Triple Bond. R. Schrock, M. Churchill 2:00—92. Heterobimetallic Complexes for Catalysis. S. tttel, J. Mayer, S. McLain, A. Janowicz, R. Baker 3:00—93. Chemistry of Oxide-Bound Transition Metal Complexes. N. Kitajima, J. Schwartz 4:00—94. C-H and C-Hal Bond Activation by Iridium Complexes. R. Crabtree, M. Burk, A. Habib, M. Lavin, E. Holt, S. Morehouse, R. Uriarte

Physical Organic Chemistry TUESDAY MORNING & AFTERNOON

TUESDAY

MORNING

Gonzaga Hall Symposium on Medicinal Chemistry M. Tishler, Presiding

Bannow Hall, Room 253 General Session 9:00—35. Patents as a Source of Chemical and Engineering Information 1984. C. Karolow 9:30—36. Molecular Geometry Calculations and Graphics with a Microcomputer. D. Relyea 10:00—37. Fuel Additives and Modification of Combustion Products—a Computer Modeling. D. Rathnamma

2:00—62. Report Card on the Waste of the 1970s—PCBs in the Environment. R. Brownell 3:00—63. Scientist and Lawyer—a Partnership in Resolving Hazardous Waste Litigation. R.Janke 4:00—64. Institutional and Economic Aspects of Hazardous Wastes. A. Kneese

Bannow Hall, Room 131 General Session

W. Bailey, Presiding

9:00—95. Reinvestigation of the Reactive Intermediate in the Synthesis of 2-Aryl-7(Supported by Pfizer, Miles Laboratories, ACS Carbethoxy - 5H-1,3,4-Oxadiazolo[3,2-a]Division of Medicinal Chemistry) Pyrimidin-5-one. B. Bhattacharya 9:00—77. Proteases: Their Role in Disease 9:25—96. Organostannanes as Precursors to and the Design of Specific Inhibitors. J. C. Organic Compounds Labeled with AstaPowers tine-211. R. Milius, W. McLaughlin, J. 9:45—78. Chemical Studies on Leukotrienes. Carroll, S. Adelstein, R. Lambrecht, S. D. Clark Mirzadeh, A. Wolf, W. Bloomer 10:30—79. Monobactams: the Discovery, 9:50—97. Chemistry of the Vinylidene Ligand Chemistry, and Antibacterial Activity of on CpMn(CO)2. L. Lewis, K. Caulton Monobactams and Their Alternately Acti10:15—98. Product Distribution in the Phovated Analogs. C. Cimarusti tobromination of Mono-Substituted Aro11:15—80. Cancer Chemotherapy: an Asmatics. L. Korona, E. Jahngen, K. Kolb. sessment of Current Progress and Future Directions. R. Handschumacher

April 23, 1984 C&EN

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Meetings 10:40—99. Radical Cations as Intermediates in Aromatic Substitution Reactions. R. O'Malley, L. Barinelli, D. Turner, J. Roman, D. Bryan 11:15—100. Evidence for Radical Intermediates in the Reactions of Sulfuric and Carboxylic Acid Esters of N-Hydroxy-NArylacetamides. M. Novak, B. Brodeur 11:30—101. Reactions of ferf-Butyllithium with 6-Halo-1-Hexenes. J. Patricia, W. Bailey 11:55—102. Chemistry and Synthesis of Macrocyclic Triamine-Based Complexing Agents. G. Weisman, D. Vachon

10:15—120. Silyl Acetal tert-Butylmethoxyphenylsilyl Ether: a New Protective Group for the Hydroxyl Function. Y. Guindon, C. Yoakim, R. Fortin, J. W. Gillard 10:40—121. Formation of Cyclic Ethers in the Double Baeyer-Villiger Oxidation of Ketals Derived from Cyclic Ketones. J. Bischoff, W. Bailev 11:05—122. Synthesis of 7-Methylimidazo[4,5-d]-/4S-Triazine-3-one and Its Covalent