SEARLE CORPORATION - Analytical Chemistry (ACS

May 23, 2012 - AMERSHAM/SEARLE CORPORATION. Anal. Chem. , 1969, 41 (4), pp 41A–41A. DOI: 10.1021/ac60273a735. Publication Date: April 1969...
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AssayjOJ " way smoothly through the enzyme maze. With radiochemicals

First—to those of you already performing enzyme assays—a summary of the advantages of the radiochemical methods of assay.

at high d i l u t i o n , of l o w levels of enzyme activity, of microgram quantities of tissue, of enzymes in the presence of inhibitors such as drugs.

Speed. S a m p l i n g and separation techniques are rapid, simple, easily performed.

S e c o n d l y — i f you are now using the radiochemical method of enzyme assay—a w o r d or two about the Amersham/Searle labelled substrates especially prepared for enzyme assay.

Specificity. W i t h the proper substrate, interference reactions can be avoided. The radiochemical method of assay is thus eminently suitable for enzymes in crude extracts, and for studying effects of inhibitors, activators, and pH. Sensitivity. W h i c h permits radiochemical assays of crude-tissue extracts

Accurately measured specific activities. A critical, documented characteristic of the labelled substrates from Amersham/ Searle. Low specific activity. Insuring high chemical and radiochemical purity. Further, low specific activity gives Amer-

2000 NUCLEAR DRIVE

DES PLAINES, ILLINOIS 60018

sham/Searle labelled substrates long

shelf-life. Low cost. A large number of enzyme assays can be performed w i t h a small amount of labelled substrate. Detailed technical information. Ranging from the precise analytical results accompanying each Amersham/Searle c o m p o u n d to the objective discussion contained in the publication "Radiochemical Methods of Enzyme Assay," copies of which are furnished on request. Call or write for specific information on labelled substrates for enzyme assay. (Do you have your copy of our 69/70 Radiochemical Catalog?) ·>-«>

TELEPHONE: (312) 2%-IOSÇ

Amersham/Searle AMER5HAM/SEARLE COKFORATION AN ACTIVITY OF G. D. StARLE A CO. AND THE RADIOCHEMICAL CENTRE

Circle No. 91 on Readers' Service Card VOL. 4 1 , NO. 4 , A P R I L 1 9 6 9

.

41 A