Selective Toxicity (Albert, Adrien) - Journal of ... - ACS Publications

Selective Toxicity (Albert, Adrien). Lionel Joseph. J. Chem. Educ. , 1952, 29 (2), p 108. DOI: 10.1021/ed029p108.1. Publication Date: February 1952. V...
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JOURNAL OF CHEMICAL EDUCATION heterocyclic compounds, and n h u t 32 to the hydronromatic compounds and the steroids. This allotmmt of iipacc is indicative of thc x u t h d s o w r - ~ l Il ~ C H I I O I Ioi I I Ithe 4 jrcr m~trcr. The rather inconsistent use of symbols may annoy some readers. In the graphical formulas of the olefins the point of unsaturation is often indicated bv two dots. and in other cases bv the so-called double hand. -4 s k i l a r obtains in the d i h & m of the acetylenic compounds. The proton is usually designated in the conventional manner. However, on page 77 a superscript dot is used instead of a positive sign. Radicals are often written by placing a dash perpendicular to the symbol, while at other times nothing is next to the symbol. On page 115, in the symbolic representation of Kharaseh's abnormal addition to olefms, the unpaired electrons are indicated by an X. This procedure is used also an pages 413 and 415. However, since the format of the structural formulas is similar to that in Beilstein most readers should have few difficulties. Some readers may consider certain sections to be rather weakfor instance, the aloohols, the phenols, the aromatic nitro compounds, the carbohydrates, and the index. The structural formulas of the disaccharides are treated rather casually. In the case of cellobiose and sucrose the stereochemistry within the monosaccharide fragments is ignored completely. Because the text is in German it will he used infrequently as a textbook in this country. However, many teachers and advanced students may wish, and perhaps should have, a copy in their libraries. The book offers an excellent opportunity for students to gain facility in the use of German, since the text contains essentially familiar material. DONALD C. GREGG Umvnnsrrr o~ Veh-uoal Buslnro~olr.Vmn~0x.r

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SELECTIVE TOXICITY

Adrien AIbert, Professor of Medical Chemistry, The Australian National University, and Honorary Lecturer in the Department of Chemistry, University College, London. Methuen & Co., Ltd.. 228 London; John Wiley B Sons, Inc., New York, 1951. xiii pp. 5 plates. 31 figs. 27 tables. 11 X 17.5 cm. $1.75.

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INTHIS book the author has presented an interesting and well written discussion of a subject that has long needed integration. The book is based on postgraduate lectures delivered to research workers and students in biochemistry, medicine, chemistry, veterinary science, and agriculture. It should appeal not only to these but also to the general reader in the more advnncrrl~dii~i~linrs in thc phyriwl aml nsturnl a:i~ncrs. Selertiw toxicity is defined as 11.t m~ivirypowwed by rr