Sniff the sweet smell of success. Aluminum alkyls for fragrances, vitamins and pharmaceuticals. Organoluminum compounds find wide application in the chemical industry. They are used as catalysts for the polymerization and oligomerization of mono-olefins and dienes, as reducing and alkylating reagents, as chemical intermediates for detergents and plasticizers, as well as for other applications. Shown below are three specific reactions illustrative of aluminum alkyls' reducing capabilities. To learn more about these reactions as well as other examples of aluminum alkyls in organic reactions
including alkylations, hydrocyanations, and more reductions, write for our new brochure, "The Use of Aluminum Alkyls in Organic ,Synthesis" on your company letterhead. Address requests to: Ethyl Corporation, Industrial Chemicals Division, Ethyl Tower, 451 Florida, Baton Rouge, Louisiana 70801.
Ethyl Corporation { mam Industrial Chemicals Division
Sodium borohydride has been used in this reduction, with yields of about 65%. A yield approaching 90% is achieved when DIBAH or TIB A is applied, utilizing all three groups on aluminum. K. Ziegler et al., Justus Liebigs Ann. Chem. 623, 9 (1959).
The reduction of nitriles to aldehydes with DIBAH is reported in a synthesis of vitamin A. Yields of polyconjugated aldehydes are practically quantitative. Philips-Duphar, British Patent 813,517; Chem. Abstr. 53,22068g ( 1959) ; cf. "Uîlmann's Encyclopedia of Technical Chemistry", Vol. 18, 1967, p. 232.
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Cost-effectiveness of DIBAH is claimed to be superior to that of lithium aluminum hydride in the reduction of steroidal 11-keto
