Software
Working Safely in the Chemistry Laboratory Here in one volume is the latest infor mation on every aspect of laboratory work-from researching assignments to calculating and reporting results. Learn how to design and build the necessary equipment, work in the labo ratory with maximum safety and effi ciency, do calculations easily and correctly, present meaningful results, and suggest further work. Whether used as a text or a work bench reference. Working Safely in the Chemistry Laboratory is an indispens able tool for anyone who works in a chemical laboratory or pilot plant.
CONTENTS First Aid Safe Practices in the Laboratory Fire Safety Toxic Chemicals Electrical Hazards Radiation Hazards Laboratory Xotebooks Aids for Calculations Use and Interpretation of Data Shop Practices Specifications Testing Chemical Literature and the Library Harry G. Hajian, Sr. and Robert L. Pecsok 270 pages(1994) Clothbound: ISBN 0-8412-2706-3 $59.95 Paperbound: ISBN 0-8412-2707-1 $39.95
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588 A
A section devoted to chiral chromatography is included.
mixed success with the printer interface. As often as not, I was kicked out of Win dows when I tried to print a table or the results from one of the special calculation or column selection routines. Sometimes it was necessary to reboot the computer to get back into Windows and resume work. When I successfully sent something to the printer, I found that the columns of the printed tables did not line up properly. The information provided in the HPLCTP5 program is accurate, concise, and extremely well organized. Although the words do not differ much from what might appear in a well-written text, the integrated graphics (especially the anima tion sequences) add something that can not be duplicated on paper. I particularly liked the animation of the band-broaden ing processes, which brought to life some concepts that do not come across espe cially well in 2D diagrams. The effect of flow rate on mass transfer is dramatically demonstrated by user-selected changes in the (simulated) flow rate. One or two potentially confusing uses of terminology were noted. The term "dead volume" refers sometimes to the column void volume and sometimes (in cluding in the glossary definition) to the system's extracolumn delay volume. In addition, the glossary definition of theoret ical plates refers to "baseline peak width" but probably should refer to the "tangentdefined baseline peak width" because var ious peak widths may be used to deter mine the plate count. Although application examples are provided for each mode of chromatogra phy, they do not always flow naturally from the instructional content of the chap ter. For example, most of the applications of paired ion chromatography use pairing agents that are not discussed in the chap ter. In the section on chiral chromatogra phy, the applications focus exclusively on Pirkle-type columns, and practical advice
Analytical Chemistry, Vol. 66, No. 10, May 15, 1994
within the chapter (e.g., column storage recommendations) also seems to be tai lored to these columns. HPLC-TP5 provides an excellent over view of the various modes of chromatog raphy for someone who has done a bit of chromatography, or perhaps for someone who has specialized entirely in one mode and wants to become familiar with the basic concepts underlying the other avail able modes. I don't believe that the pack age provides enough depth on any given topic to enable the user to head off to the lab and try a new mode of chromatogra phy. Additional reading and training would be required. The program is strongest in its presen tation of fundamental concepts. Practical and applications-related information is not nearly as extensive; thus, the program has limited impact on training for actual labo ratory operations. A computerized deci sion tree is included to assist the user in selecting from among the modes of chro matography on the basis of sample prop erties (solubility, molecular weight, ρΚ.Λ, etc.), but the advice resulting from this exercise is only a column/eluent combina tion that would require considerable ex perimental refinement in the laboratory. The program's advice might be used as the starting point for other available meth ods development software packages such as DryLab (LC Resources, Orinda, CA). HPLC-TP5 provides a useful and valu able training tool for those needing an overview of the various modes of HPLC. Considering that Phenomenex has made the program available at a very reasonable price (when ordered in combination with its products), I would recommend that this program be added to the training re sources of academia and industry. Reviewed by F. Vincent Warren, BristolMyers Squibb, New Brunswick, NJ
SOFTWARE RELEASED CE Database Perkin Elmer 761 Main Ave. Norwalk, CT 06859-0310 800-345-5224, 203-762-1000 $225
CE Database provides access to almost 1400 published references on CE research and applications. Citations include author, title, journal, date of publication, and se lected key words. It is available in Macin tosh and DOS formats.
