Stable carbocations. CLXIV. Relative ability of charge delocalization

May 1, 1974 - Mark Schormann, Shaun Garratt, and Manfred Bochmann ... G. K. Surya Prakash, Chulsung Bae, Golam Rasul, and George A. Olah...
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3548 over 95% of the material. Attempts to isolate the product bromide were frustrated by rapid dehydrohalogenation. Procedure for Kinetic Runs for the Reaction of Bromotrichloromethane with the 4-Methyl-l-phenyl-4-(substituted pheny1)pentanes. Attempted analyses by gas-liquid chromatography were unsuccessful. The brominated hydrocarbons formed as products decomposed under analytical conditions and the decomposition products eluted with the starting material. The error thus introduced made such analyses useless. Analysis of the mixtures, both before and after reaction, was carried out ciu nmr spectroscopy. Some part of the spectra that did not change during the reaction, usually the methyl singlet at approximately 6 1.15, was used as an internal standard. The disappearance of the benzylic proton triplet of the 4-methyl-1-phenyl4-(substituted pheny1)pentane and the benzylic proton singlet of diphenylmethane was used to determine the relative rates. Solutions of a 4-methyl-1-phenyl-4-(4-substitutedpheny1)pentane. diphenylmethane, and bromotrichloromethane were prepared in the approximate molar ratios of 1 :2:30. Approximately 0.75 ml of the solution was put in each of several Pyrex ampoules. The ampoules were cooled to Dry Ice-acetone temperature, evacuated, filled with nitrogen gas, and then warmed to room temperature. This process was repeated three times. After cooling and evacuation, the tubes were sealed. One ampoule was reserved for analysis of starting materials; the remainder were placed horizontally just

below the surface of a mineral oil constant temperature bath maintained at 70.0 f 0.5". The samples were irradiated with ultraviolet light provided by a Ken-Rad 275-W sunlamp placed 20 cm above the surface of the oil. Reaction times varied from 3 to 5 hr, by which time 30 to 60% of the total hydrocarbons had reacted. The ampoules were then cooled and opened. All determinations were run in replicate. Procedure for Kinetic Runs for the Reaction of Bromotrichloromethane with the 4-Phenyl-1-substituted Butanes. Solutions of 4-phenyl-1-substituted butanes, diphenylmethane, and bromotrichloromethane were prepared in the approximate molar ratio of 1 : 1 :10. Analysis of the mixture both before and after reaction was carried out cia nmr spectroscopy. Some part of the spectrum that did not change in integration during the reaction, usually all or part of the nonbenzylic aliphatic part of the spectrum, was used as an internal standard. The disappearances of the benzylic triplet of the 4-phenyl-1-substituted butane and the benzylic singlet of the diphenylmethane were used t o determine the relative rates of reaction. In all other ways the procedure was the same as outlined above. Determination of Relative Rates of Hydrogen Abstraction. The ratios of the relative rate constants were obtained using the usual competitive procedures. a 4 (34) G. J. Gleicher, J . Org. Chem., 33,332 (1968).

Stable Carbocations. CLXIV.' The Relative Ability of Charge Delocalization by Phenyl, Cyclopropyl, and Methyl Groups in Carbenium Ions George A. Olah,* Philip W. Westerman,2and Jun Nishimura2

Contribution from the Department of Chemistry, Case Western Reserve University, Cleueland, Ohio 44106. Received October 17, 1973 Abstract: The relative order of charge delocalization by neighboring phenyl, cyclopropyl, and methyl groups in

related series of stable, long-lived carbocations was studied by 13Cnmr spectroscopy. The decreasing order of charge delocalization was generally found to be Ph > c-Pr > CH3. The results are interpreted in terms of differentiating delocalization in the intermediate ions (as measured by cmr spectroscopy) from participation of the same groups, showing the decreasing order c-Pr > Ph > CH3, in solvolytic reactions. The latter is obviously affected by the energy differences in the case of the more strained ground state of the precursor esters as compared to the less strained carbenium ion like transition states. Some electrophilic addition reactions to phenylcyclopropyl-substituted ethenes proceeding cia carbenium ion like transition states show comparable results to the solvolysis studies. A number of carbocations have also been studied in which phenyl, methyl, and cyclopropyl groups are potentially capable of competing with each other to stabilize an adjacent carbenium ion center.

T

he ability of a cyclopropyl group to stabilize an adjacent carbocation center is well documented. It has been stated* from measurements of tricyclopropylcarbenium ion-tricyclopropylmethyl alcohol and triphenylcarbenium ion-triphenylmethyl alcohol equilibria that the cyclopropyl group is capable of stabilizing an adjacent carbocation center to a greater degree than a phenyl group. From a consideration of the relative rates of solvolysis of p-phenyl- and -cyclopropyl-tert-

cumyl chlorides, and the esters RMe2COPNB(R = Ph, c-GHS), Brown and Peters5 also concluded that the cyclopropyl group is more electron releasing than the phenyl group. In contrast to the above, on the basis of the chemial shifts of the carbenium ion centers in the phenyldimethylcarbenium ion,sa,b the cyclopropyldimethylcarbenium ion,eemd and the trimethylcarbenium ion,6e in our preceding studies we concluded6' that the relative

(1) (a) Part CLXIII: G. A. Olah, P. Schilling, J. M. Bollinger, and J . Nishimura, J. Amer. Chem. Soc., 96, 2221 (1974); (b) Preliminary communication: G. A. Olah and P. W. Westerman, ibid., 95, 7530 (1973). (2) Postdoctoral Research Associates 1971-1973. (3) For recent reviews, see (a) I c-Pr- > CH3-

Because the solvolytic (and equilibrium) measurements and nmr spectral results lead t o diflerent conclusions, we decided to examine this apparent discrepancy in greater detail. We would like first to point out that solvolytic rates and equilibrium constants are only giving indication of energy differences between ion and precursor, whereas 13C chemical shifts are a direct function of the carbocations and thus can be expected t o reflect their properties. The two approaches therefore measure on a different basis. It is entirely feasible that the cyclopropyl group is a better participating group in solvolysis than phenyl but the phenyl group in the intermediate ions delocalizes charge away from the carbocation center better than the cyclopropyl group. In our studies, three experimental approaches have been followed. (A) The complete proton decoupled carbon-13 nmr spectra of a comprehensive series of methyl, phenyl, and cyclopropyl substituted carbenium ions have been obtained at low temperature and in solvents of low nucleophilicity. Although the pmr spectroscopic data of comparable cyclopropyl and phenyl substituted ions also could be used to deduce the relative delocalizing abilities of phenyl and cyclopropyl groups, we believe that the I3Cdata are more reliable for the following reasons. The center of greatest electron deficiency in the carbocation, rather than just the positions a or P to it as in 'H nmr spectroscopy, may be observed directly by I3Cnmr spectroscopy; solvent and anisotropy effects are comparably smaller than change polarization effects on the I3C shift, whereas this is not necessarily true for the 'H shift. In addition, the cmr spectra of related protonated cyclopropyl ketones and their parent compounds have been measured. (B) Olah, et al.

Carbocations have been prepared, in which phenyl, methyl, and cyclopropyl groups are potentially capable of competing with each other to stabilize an adjacent carbenium ion center. Similar competitive type experiments have been reported recently by S ~ r e n s e n . ~(C) Some electrophilic addition reactions to phenylcyclopropyl-substituted ethenes, proceeding cia carbenium ion like transition states, were studied to determine the relative directive effects of phenyl and cyclopropyl groups. Experimental approaches B and C should give measures of the delocalization ability, which are the same as those involved in solvolysis reactions. That is the same structural changes should be experienced by the cyclopropyl, phenyl, and methyl groups in the equilibria and addition reactions as are involved in the solvolysis processes. Results and Discussion

(A) Carbon-13 Nmr Spectroscopic Studies. The complete proton decoupled carbon-13 nmr spectra of a series of methyl-, phenyl-, and cyclopropylcarbenium ions, as well as their precursors, were obtained by the Fourier transform method. The assignment of signals was made by the usual methods,8 which included "off-resonance" decoupling experiments, considerations of relative signal intensities and molecular symmetry, and the observation that polar groups exert a large inductive effect on the shifts of directly attached carbons. Data are summarized in Table I, with those of related precursors shown in Table 11. Chemical shifts for related protonated methyl, phenyl, and cyclopropyl ketones and their parent compounds are shown in (7) (a) T. S. Sorensen, I. J. Miller, and K. Ranganayakulu, Aust. J . Chem., 26, 311 (1973); (b) T. S. Sorensen, J. Amer. Chem. Soc., 89, 3794 (1967). (8) (a) D. M. Grant and E. G. Paul, J . Amer. Chem. Soc., 86, 2984 (1964); (b) D. I > * ~ 193.8. Some spectra were obtained using a Varian Associates Model HA-100 equipped with a Fourier transform accessory (V-4357 pulsing and control unit), broad-band proton decoupler, and variable temperature probe. The instrument, lock, and referencing systems have been described in more detail elsewhere. 4 1

Acknowledgment. Support of our work by the National Science Foundation is gratefully acknowledged. (41) G. A. Olah. G . Liang, and P. W. Westerman, J . Amer. Chem. Soc., 95,3698 (1973).

Charge Delocalization by Phenyl, Cyclopropyl, and Methyl Groups