Stereoselective Hydrocoupling of Cinnamic Acid Esters by Electroreduction: Application to Asymmetric Synthesis of Hydrodimers Naoki Kise,* Shumei Iitaka, Keisuke Iwasaki, and Nasuo Ueda Department of Biotechnology, Faculty of Engineering, Tottori University, Koyama, Tottori 680-8552, Japan
[email protected] Received July 11, 2002
The electroreduction of Ar-substituted methyl cinnamates in acetonitrile gave all-trans cyclized hydrodimers stereoselectively (58∼90% de). In all cases, small amounts (
