Mar 23, 1971 - It was introduced as an antisyphilitic agent2 but while being administered for that purpose it was found to have diuretic properties3 g...
Structure of the diuretic merbaphen. E. M. Schultz, J. B. Bicking, S. J. DeSolms, and G. E. Stokker. J. Med. Chem. , 1971, 14 (10), pp 998â999. DOI: 10.1021/ ...
spironolactone. In regard to diuretic-induced hyperuricemia, the discovery in ... All mice were administered 1 ml of 0 .9Ð saline orally and either simultaneously ... 30, 45 and 60 minutes; color was developed by the addition of 0.05 ml of 0.1 M ...
3. 5. Ethacrynic Acid. 0. 5. aPresented as scores; assay protocols are described in the text, and scoring ... with an indwelling bladder catheter and primed with creatinine ...... Na , 4.8; Î , 6.3; and Cl", 6.3 mEq/dog and urine volume, 210 ml/dog.
May 1, 2002 - Louis L. Skaletzky, B. E. Graham, and Jacob Szmuszkovicz. J. Med. Chem. , 1969, 12 (6), pp 977â988. DOI: 10.1021/jm00306a004. Publication ...
Relation between structure, stereochemistry, and diuretic activity in the 2-amino-.alpha.-phenylcyclohexanemethanol series, a new class of diuretic agents. II.
A series of1,3-amino alcohols and 1,3-amino ethers were made for diuretic testing. The four diastereo- isomers of both the alcohols and methyl ethers (I, R =.
8-Chloroalloxazine, A New Diuretic. Synthesis and Structure. HAROLD G. PETERING, and GARRETT J. VAN GIESSEN. J. Org. Chem. , 1961, 26 (8), pp 2818â ...
Pteridines related to the diuretic, 2,4-diamino-6,7-dimethylpteridine. Joseph Weinstock, Roberta Y. Dunoff, Joyce E. Carevic, June G. Williams, and Anthony J.
Synthesis and diuretic activity of 2-amino-4-arylamino-6-mercapto-s-triazines and related derivatives. Madhusudan H. Shah, Chimanlal V. Deliwala, U. K. Sheth.
998 Journal of Medicinal Chemistry, Ik7'1, Vol. 14, .\-o. 10
