March, 1030
-1-53
HALOGENATED SULFANILAMIDOHETEROCYCLES
Anal. Calcd. for C6HliOzN: N, 10.84. Found: X, 10.60. Acid Hydrolysis: (A) dl-a-Aminononanoic Acid.--A solution of 22.2 g. of diethyl n-heptylacetamidomalonate in 100 ml. of concentrated hydrochloric acid was refluxed for seven hours and then cooled t o 0". There was thus precipitated a mass of shiny pearly plates. This material was collected b y filtration and dried yielding 10.7 g. of amino acid hydrochloride. The crude product was dissolved in a mixture of ethanol and water ( 1 : l ) and the amino acid precipitated by the addition of 15 ml. of pyridine. The product was filtered, washed and air dried; yield 6.7 g. (55: I . I t was further purified with little or no loss by solutior- in
