Studies on Arginine Peptides. III. On the Structure of Tricarbobenzoxy

III. On the Structure of Tricarbobenzoxy-L-arginine1. Leonidas Zervas, Milton Winitz, and Jesse P. Greenstein. J. Am. Chem. Soc. , 1961, 83 (15), pp 3...
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LEOXIDAS ZERVAS, I I I L T O N

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Appendix 11

J. P.GREENSTEIN

1'01. s3

Since

Denaturation and Change in Hydrogen-ion Binding.LVhen, in a certain PN-range, the ratio of native to denatured molecules is pH-dependent, denaturation must be accornpanied by a change in the average number of hydrogen ions dissociated from the protein molecules, Using equation Y, A11 of the precedinypaper,4 we hdve

dy/dPH = -2.303 dy/d In H = -2.303 (dyld In Kut,a,i.) ( d In I