Styrene Oxide Adducts in an Oligodeoxynucleotide Containing the

Containing the Human N-ras Codon 12: Minor Groove ... Thomas M. Harris, and Michael P. Stone* ... in the codon 12 sequence of the human N-ras protoon-.

position G6 in the ras12 oligodeoxynucleotide. Solution ... This was conceptually similar to an .... same residue, on the basis of the assumption that, for a B-like.

... from G·C to A·T, while the base pair 3' to the lesion was changed from T·A to G·C. ... Minor Groove Orientation for the (1S,2R,3S,4R)-N- [1-(1,2,3,4-Tetrahydro-2,3 ... Tommy N. Johansen, R. Stephen Lloyd, Constance M. Harris, Thomas M.

Michael P. Stone*. Center for .... induced perturbations of DNA containing the ras codon 12 ... sequence of the human n-ras protooncogene at codon 12.

Smaller minor groove disturbances were observed for the S(12,2) adduct, which had the styrene ring oriented flat in the minor groove. No DNA bending was ...

NOE and chemical shift data suggested that the styrenyl moiety was oriented in the minor groove and in the 3'-direction from the site of adduction. In contrast, this change in ... Label-Free and Selective Photoelectrochemical Detection of Chemical DN

Feloora R. Setayesh,† Bart L. DeCorte,§ Pamela Horton, Constance M. Harris, ... L., Harris, C. M., Harris, T. M., and Stone, M. P. (1996) Biochemistry 35, ...

Michael S. Kuska , Aaron A. Witham , Michael Sproviero , Richard A. Manderville ... S. Wilkinson, Constance M. Harris, Thomas M. Harris, and Michael P. Stone.

Structure of an Oligodeoxynucleotide Containing a Butadiene Oxide-Derived N1 ... Tandace A. Scholdberg, W. Keither Merritt, Stephen M. Dean, Agnieska ...

Department of Chemistry, Center in Molecular Toxicology, Vanderbilt-Ingram ... and Center for Research on EnVironmental and Occupational Toxicology, ...