Substrate Specificity and Stereoselectivity of Rat Brain Microsomal

Pusheng Fan, Khaled Abouzid, Zhaoxing Meng,. Diane Biegel, and ... Chart 2. Structures of Cannabimimetic Ligands Tested as Enzyme Inhibitors. 1682. J...
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1682

J. Med. Chem. 1999, 42, 1682

Additions and Corrections 1998, Volume 41 Hairuo Peng, Leon H. Zalkow,* Robert T. Abraham, and Garth Powis: Novel CDC25A Phosphatase Inhibitors from Pyrolysis of 3-R-Azido-B-homo6-oxa-4-cholesten-7-one on Silica Gel. Page 4678. In Table 1, the chemical shifts of compounds 3 and 4 should be switched: compound 3, 1.43, s; compound 4, 1.34, s. Page 4678. In Results and Discussion, paragraph 2, line 6, ring A should be replaced by ring B: ...opening of ring B to give B,... Page 4679. In Table 2, the IC50’s of compounds 3 and 4 should be switched: compound 3, >50a; compound 4, 13.3a. JM990020F 10.1021/jm990020f Published on Web 03/17/99

1999, Volume 42 Wensheng Lang, Ce Qin, Sonyuan Lin, Atmaram D. Khanolkar, Andreas Goutopoulos, Pusheng Fan, Khaled Abouzid, Zhaoxing Meng, Diane Biegel, and Alexandros Makriyannis*: Substrate Specificity and Stereoselectivity of Rat Brain Microsomal Anandamide Amidohydrolase. Page 900. The structure of SR141716A in Chart 2 is incorrect. This compound has a piperazine ring (not a morpholine ring). The corrected Chart 2 appears below. Chart 2. Structures of Cannabimimetic Ligands Tested as Enzyme Inhibitors

JM990139O 10.1021/jm990139o Published on Web 04/15/99