NOTES
May 5, 1952 OH
2435
acetic acid from benzoic a ~ i d - 1 - C ' ~was accomplished by the following sequence of reactions
Cl OH
OH =*-OH -
NaOCHo P
BrCHzCOOCHo
Hz0
NaOH
90%
~ * - - O C H ~ C O OH sozc12 + HOAc
75% Hexachlorophene-C14 (m.p. 166-167') cor.) was c1 isolated in a 59.6% over-all chemical yield as two / crops, in the second of which 12.5% was recovered C I ~ * - O C H ~ C O O H with carrier; specificactivity (of undiluted product) : 3.58 X lo8 ( f4.6a/0) ~ts./min./rnM.~;specific The concentration of the sulfuric acid employed activity of starting formaldehyde-C14: 3.52 x lo8 (d=4.4%) ~ts./min./mM.~;radiochemical yield: in the Schmidt reaction with benzoic acid plays a significant role in determining the yield of aniline. 60.6 f 3.9%. In Table I are summarized the results observed (3) Counted as a film (
