Synthesis of 5-azacytidine-6-13C and-6-14C

Jun 23, 1976 - (10) R. A. Scherrer, C. V. Winder, and F. W. Short, Abstracts of the 9thNational Medicinal Chemistry Symposium of the. American Chemica...
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598 Journal of Medicinal Chemistry, 1977, Vol. 20, No.4

(6) M. S. Newman, J. Am. Chenz. Soc., 60, 2947 (1938). (7) C. V. Winder, cJ. Wax, V. Burr, M. Been, and C. E. Rosiere, .4rch. l n t . Pharmucodyra. Ther., 116. 261 (1958). (8) G. Wilhelmi, Schweiz. M e d . Wochenschr., 79, S77 (1949). (9) D. *J. Finney, R. Latscha, R. M.Bennett, and P. Hsu, Tables for Testing Significance in a 2 X 2 Contingency Table", Cambridge University Press, New York, N.Y., 1963. (10) R. A. Scherrer, C. V. Winder, and F'. W.Short, Ahstracts of the 9th National Medicinal Chemistry Symposium ~f the American Chemical Society. Minneapolis, Minn., June 1964, p l l a -i. (11) T. 1 '. Shen, I n t . S y m p . Non-Steroidul Antiinf/ammcitorj, l h g s , Proc., 1964, 13 (1965).

Notes

(12) S. Wong, Annu. R e p . M e d . Chem., 10, 172 (1975), and previous papers in this series. (13) R. A. Scherrer in "Antiinflammatory Agents", Vol. I, R. A. Scherrer and M. W. Whitehouse, Ed., Academic Press, New York, N.Y., 1974, pp 34-39. (14) J. T. Craig, M. A. Pitt, K. W. Tan, and A. D. Woolhouse, Aust. J . Chem., 25, 837 (1972). (15) J. S. Kaltenbronn and T. 0. Rhee, J . M e d . Chem., 17,654 (1974). (16) F. S. Spring, J . C h e m . SOC.,1332 (1934). (17) D. H. Hey and R. Wilkinson, J . C h e m . Soc., 1030 (1940). (18) M. S. Newman and J. Blum, J. Am. C h e m . SCJC., 8 6 , 503 (1 964).

Synthesis of 5-Azacytidine-&I3Cand -614C Kenneth K. Chan,' James A. Staroscik, Schools o/ Pharmuc:,, a n d hl