Synthesis of a Fragment of Human Parathyroid Hormone, hPTH-(44-68)

Because human parathyroid hormone differs from the bovine ... in ~ i v o and does not inhibit native parathyroid hormone in vitro, indicating lack of ...
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11.52 J,urnu/ uf Mpdicinul Chrmistr.), 1977. Vol 20, N o 11

Hosenblatt et a l

Synthesis of a Fragment of Human Parathyroid Hormone, hPTH-(44-68) Michael Rosenblatt, Henry T. Keutmann, Geoffrey W. ‘I’regear, and John T. Potts, Jr.* 1 he 6ndocrLne [.nit, Massachusetts General Hospital, and Uepartnwnt of Medicine, Harvurd Medical School, R o i t m hfassurhusettq 02114. Received Februarj 7, 1977

3,25 amino acid peptide representing an internal region of human parathyroid hormone, hPTH-(4448),was synthesized hy the solid-phase method. This region was synthesized to obtain antisera against the carboxy-terminal two-thirds