Synthesis of Propionate Motifs: Diastereoselective Tandem Reactions

Jan 2, 2002 - Yvan Guindon*,Karine Houde,Michel Prévost,Benoit Cardinal-David,Serge R. Landry,Benoit Daoust,Mohammed Bencheqroun, andBrigitte ...
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Synthesis of Propionate Motifs: Diastereoselective Tandem Reactions Involving Anionic and Free Radical Based Processes [J. Am. Chem. Soc. 2001, 123 (35), 8496-8501]. Yvan Guindon*, Karine Houde, Michel Pre´ vost, Benoit Cardinal-David, Serge R. Landry, Benoit Daoust, Mohammed Bencheqroun, and Brigitte Gue´ rin Page 8499: In the footnote of Table 1, P ) TBDMS should read P ) TBDPS. Page 8501: In the General Procedure for Radical Reduction or Allylation under Chelation-Controlled Conditions, it should be noted that iPr2NEt was used only for the radical reductions with Me2AlCl and not for the allylations, where the use of a base inhibits the reaction (starting material was recovered). For the allylation reactions, it should be mentioned that after the addition of Me2AlCl, the reaction mixture was exposed to air (O2) 10 min prior to the first addition of Et3B. Each addition of Et3B was followed by 20 mL of air. In the Supporting Information, the Rf value for 2b should be 0.03, while the Rf value for compounds 2a, 3a, and 3b should be 0.23. JA015131U 10.1021/ja015131u Published on Web 01/02/2002