Serving the chemical, life sciences, and laboratory worlds
VOLUME 91, NUMBER 8 FEBRUARY 25, 2013
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JOHN C. LECHLEITER
C&EN talks with the Eli Lilly & Co. CEO about turning the company around.
GOVERNMENT & POLICY 23 24
CONCENTRATES EXPLOSIVE DILEMMA
Pakistani fertilizer plant project in Indiana has been suspended because of Afghan bomb link.
COVER STORY
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SAVING ENDANGERED PHOTOS Triggered by cases of fraud, the science of photo conservation and authentication is blossoming. PAGE 9
AVIAN FLU STUDIES STALLED
U.S. funds to support research are on hold while guidelines are debated.
SCIENCE & TECHNOLOGY 28 30
CONCENTRATES CHEMISTS SHARE #REALTIMECHEM
Twitter hashtag connects a worldwide community.
QUOTE OF THE WEEK “Fifty-five percent of drugs used in America don’t work for the patients they are prescribed for.”
NEWS OF THE WEEK 4
Federal R&D agencies explain just what would be lost on March 1. 5
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SUPREME COURT HEARS AG BIO CASE
ACS NATIONAL AWARDS 38
2013 WINNERS
Betley, Burke, Ediger, Evans, Haire, Jonas, Palmer, and Richmond.
CONGRESS REOPENS PUBLIC ACCESS
House, Senate bills go further than past efforts to broaden access to taxpayer-funded research. 6
WHY SN2 REACTIONS FAIL IN WATER
Cluster study shows progress of reaction is impeded by presence of just three water molecules.
PEPTIDE THAT SAYS “DON’T EAT ME”
Justices seem friendly to Monsanto’s patent rights and self-replicating technologies. 6
FLOURISHING FLUORINE
Field continues its rapid growth with a new round of simple, efficient reactions.
Nanoparticles tagged with the synthetic model of key human protein evade the immune system.
G. STEVEN BURRILL, CHIEF EXECUTIVE OFFICER, BURRILL & CO. PAGE 17
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SEQUESTER BUDGET CUTS DETAILED
CELL PAPER RETRACTED, REPLACED
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Former MIT postdoc accused of falsifying data; lab publishes a better version of synapse imaging method. 7
FIGHTING FLU DRUG RESISTANCE
New family of inhibitors may help prevent drugresistant flu strains from arising.
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GOOD NEWS AT INFORMEX ...
Fine and custom chemical executives report strong sector, return of business from Asia. 8
... BUT BAD NEWS FROM EUROPE
Region’s economic recession continues to bedevil chemical manufacturers. 8
FIRST LOOK AT FEBRUARY METEOR
Interstellar object that exploded over Russia on Feb. 15 was a 10,000-ton chondrite, experts say.
BUSINESS 15 17
CONCENTRATES AFTER CLINICAL TRIALS
Pharmaceutical firms gather real-world data on patient outcomes to evaluate therapies. 20
THE DEPARTMENTS 2 3 36 37 43 45 48
LETTERS EDITOR’S PAGE ACS COMMENT ACS NEWS OBITUARIES CLASSIFIEDS NEWSCRIPTS
FEWER HUGE DEALS IN 2012
Specialty chemical acquisitions drove mergers, but total value of large deals declined.
COVER: Shutterstock/C&EN
CENEAR 91 (8) 1–48 • ISSN 0009-2347