analytical chemistry
Volume 50, No. 7, June 1978 ANCHAM 50(7) 611A-712A/833-1024 (1978) ISSN 0003-2700
© Copyright 1978 by the American Chemical Society
Permission of the American Chemical Society is granted for libraries and other users to make reprographic copies for use beyond that permitted by Sections 107 or 108 of the U.S. Copyright Law, provided that, for all articles bearing an article code, the copying organization pay the stated per-copy fee through the Copyright Clearance Center, Inc. For further information, write to Office of the Director, Books and Journals Division, ACS, 1155 16th St., N.W., Washington, D.C. 20036. Published monthly with review issue added in April and Laboratory Guide in August by the American Chemical Society, from 20th and Northampton Sts., Easton, Pa. 18042. Executive and Editorial headquarters, American Chemical Society. 1155 16th St. N.W., Washington, D.C. 20036 (202)872-4600. Second class postage paid at Washington, D.C, and at additional mailing offices.
CONTENTS REPORT A. J. Glazko, Warner-Lambert/Parke-Davis, discusses some challenging analytical problems faced during the development of assay procedures for new drugs 632 A INSTRUMENTATION Peter L. Bailey, Electronic Instruments Ltd., UK, presents the modifications to common electrochemical techniques necessary for process stream monitoring 698 A THE ANALYTICAL APPROACH Alan P. Bentz of the U.S. Coast Guard describes the role of analytical chemistry in mystery oil spill identifications 655 A
1978 Subscription prices—including surface postage 1yr
2 yr
3yr
$10.00 19.00
$18.00 36.00
$25.00 52.00
NONMEMBERS- -PERSONAL: Domestic 14.00 Foreign 23.00
26.00 44.00
38.00 65.00
INSTITUTIONAL. Domestic Canada Other foreign
26.00 44.00 54.00
38.00 65.00 77.00
MEMBERS: Domestic Foreign
14.00 23.00 29.00
Airmail and air freight rates are available from Membership & Subscription Services, ACS, P.O. 3337, Columbus, Ohio 43210 (614) 421-7230. New and renewal subscriptions should be sent with payment to the Office of the Controller at the ACS Washington address. Subscription service inquiries and changes of address (include both old and new addresses with ZIP code and recent mailing label) should be directed to the ACS Columbus address noted above. Please allow six weeks for change of address to become effective. Claims for missing numbers will not be allowed if loss was due to failure of notice of change of address to be received in the time specified; if claim is dated (a) North America: more than 90 days beyond issue date, (b) all other foreign: more than one year beyond issue date; or if the reason given is "missing from files". Microfiche subscriptions are available at the same prices but are mailed first class domestic and airmail foreign. Inquiries and payments to Microform Program, ACS Washington address. Single issues, current year, $3.00 except review issue and Labguide, $4.00; back issues and volumes; microfilm editions from volume 1 to present: write or call Special Issues Sales, ACS Washington address (202) 872-4365. Advertising Management: Centcom, Ltd., 25 Sylvan Road South, Westport, Conn. 06880 (203) 2267131
NEWS "Clinical Chemists' Role in Early Detection and Treatment of Cancer" is the topic of the Second Annual Arnold O. Beckman Conference in Clinical Chemistry, September 6-8, 1978, San Antonio. Frank A. Bovey of Bell Labs receives award 641 A BOOKS Books on statistics, integrated circuits, analysis of drugs and metabolites by GC/MS, and fractionation of synthetic polymers are reviewed by David Frazier, Timothy A. Nieman, Jack E. Wallace, and John G. Cobler 679 A EDITORS' COLUMN A drop of undiluted blood serum is analyzed by a thin-film technique developed by Eastman Kodak 695 A EDITORIAL There is justification for a wide variety in the format and organization of scientific meetings, because of the different objectives to be fulfilled 833
Technical Contents/Briefs
614 A
Letters
626 A
Meetings
642 A
Short Courses
644 A
New Products
666 A
Chemicals
672 A
Manufacturers' Literature
675 A
Advertising Index
710 A
Author Index
IBC
Future Articles
IBC
Our cover is a depiction of an electrochemical sensor in a stylized process stream
A N A L Y T I C A L CHEMISTRY, V O L . 5 0 , NO. 7, JUNE 1978 ·
613 A