ARTICLE pubs.acs.org/est
Temporal Dynamics of Periphyton Exposed to Tetracycline in Stream Mesocosms Erin L. Quinlan,† Christopher T. Nietch,‡ Karen Blocksom,† James M. Lazorchak,*,† Angela L. Batt,† Richard Griffiths,§ and Donald J. Klemm† †
Office of Research and Development, National Exposure Research Laboratory, Ecological Exposure Research Division, U.S. Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, Ohio 45268, United States ‡ Office of Research and Development, National Risk Management Research Laboratory, Water Supply Water Resources Division, U.S. EPA, 26 West Martin Luther King Drive, Cincinnati, Ohio 45268, United States § Office of Research and Development, National Risk Management Research Laboratory, Land Remediation and Pollution Control Division, U.S. EPA, 26 West Martin Luther King Drive, Cincinnati, Ohio 45268, United States
bS Supporting Information ABSTRACT: Significant amounts of antibiotics enter the environment via point and nonpoint sources. We examined the temporal dynamics of tetracycline exposure to stream periphyton and associated organisms across a logarithmically dosed-series of experimental mesocosms, designed to mimic natural conditions. Target in-stream tetracycline exposures were based on environmentally relevant concentrations in aquatic ecosystems throughout the United States (
