The Most Cited Journal in Medicinal Chemistry - C&EN Global

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Novel Compounds • Macromolecular Targets • Modeling/QSAR • Pharmacokinetics • Diagnostic Agents

2008 / Volume 51 / 24 Issues Impact Factor: 5.115 - HIGHEST EVER! Total Citations: 38,868 Indexed in PubMed/MEDLINE

Completing its 50th volume of publication in 2007, the Journal of Medicinal Chemistry publishes original research on the correlation of molecular structure to biological activity with a focus on the relationships of chemistry to biological activity. This includes design and synthesis of novel biologically active compounds, molecular modifications designed to target drugs to specific tissues, the role of metabolism in drug actions, application of NMR and X-ray crystallography to investigate molecular recognition at receptors, molecular modeling studies that furnish fresh insight into the design of novel agents, and molecular biology studies of the interaction of ligands and receptors. In addition to the rapid publication of research findings, this renowned journal also publishes Perspectives devoted to single research topics, Letters, Brief Articles, and extensive Book Review sections.

Philip S. Portoghese, Editor-in-Chief Distinguished Professor Department of Medicinal Chemistry University of Minnesota, College of Pharmacy SENIOR EDITORS Yusuf J. Abul-Hajj University of Minnesota Jürgen Bajorath University of Bonn Richard A. Glennon Virginia Commonwealth University Stephen S. Hecht University of Minnesota Laurence H. Hurley University of Arizona BOOK REVIEW EDITOR Joseph G. Cannon University of Iowa EUROPEAN EDITORS Povl Krogsgaard-Larsen The Danish University of Pharmaceutical Sciences Carlo Melchiorre University of Bologna PERSPECTIVES EDITOR William J. Greenlee Schering-Plough Research Institute

Impact Factor and citation data as reported in the 2006 Thomson Scientific Journal Citation Reports®.

Visit http://pubs.acs.org/JMC to: • View the 50th Anniversary website, featuring the top 50 most cited articles of the first 50 years of publication • View listings of current, most accessed and most cited JMC articles • Read articles ahead of the print issue as Articles ASAPSM • Read the free sample issue (Vol. 51, Iss. 1) • Sign up for E-mail Alerts and RSS Feeds • Register as an author on the ACS Paragon Plus Environment and submit your manuscript