REPORT min using blood sampling. For the 200-mg/kg dose, the half-life of elim ination was determined to be 7.8 ± 1.0 min by microdialysis and 11.1 ± 3.3 min by blood sampling. References (1) Abstracts of the Second International Symposium on Microdialysis, May 1517, 1991, Curr. Sep. 1991, 10, 66-118. (2) Microdialysis in the Neurosciences; Rob inson, T. E.; Justice, J. B., Eds.; Else vier: Amsterdam, in press. (3) Ungerstedt, C. U., U.S. Patent 4 694 832, 1987. (4) Kissinger, P. T. /. Chromatogr. Biomed. Appl. 1989, 488, 31-52. (5) Huang, T; Shoup, R. E.; Kissinger, P. T. Curr. Sep. 1990, 9, 139-43. (6) Huang, T; Shoup, R. E.; Kissinger, P. T. Curr. Sep. 1990, 10, 16-18. (7) Westerink, B.H.C.; Damsma, G.; Rollema, H.; DeVries, J. B.; Horn, A. S. Life Sci. 1987, 41, 1763-75. (8) Kendrick, K. M. Methods in Enzymot 1988, 168, 182-205. (9) Benveniste, H.; Huttemeier, P. C. Prog. Neurobiol. 1990, 35, 195-215. (10) Tossman, U. LC-GC 1991, 9(1), 4652. (11) Scott, D. O.; Sorensen, L. R.; Lunte, C. E. /. Chromatogr. 1990, 506, 41. (12) Scott, D. O.; Steele, Κ L.; Sorensen, L. R.; Lunte, C. E. /. Pharm. Res. 1991, 8, 389. (13) Steele, K. L.; Scott, D. O.; Lunte, C. E. Anal. Chim. Acta 1991, 246, 181-86.
Craig E. Lunte (center) received his B.S. degree in chemistry from the University of Mis souri-Rolla in 1979 and his Ph.D. from Purdue University in 1984. He is currently an assistant professor at the University of Kansas. His research interests include elucidating the relationship between electrochemical and biological activity in organic compounds, the development of analytical methods to study biochemical systems, and the application and theory of microdialysis perfusion. Dennis 0. Scott (right) received his B.S. degree from the University of Arkansas at Fayetteville in 1987. He is currently a Ph.D. candidate at the University of Kansas. His research interests include the development of bioanalytical methods, particularly for in vivo studies of drug metabolism, pharmacokinetics, and biologically important endog enous compounds. Peter 71 Kissinger (left) received his B.S. degree from Union College (Schenectady, NY) in 1966, and his Ph.D. from the University of North Carolina in 1970. He obtained a Fine Fellowship for postdoctoral research at the University of Kansas and began his teaching career at Michigan State University in 1972. He is professor of chemistry at Purdue University and president of Bioanalytical Systems, which he founded in 1974.
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