The nature of virus multiplication

mine content, and respiratory eneymes, are considered in Section. V by J. L. Tullis, C. S. Wright, C. A. Doan, C. F. Code, and B. Chance. In Section V...
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JOURNAL OF CHEMICAL EDUCATION

mine content, and respiratory eneymes, are considered in Section V by J. L. Tullis, C. S. Wright, C. A. Doan, C. F. Code, and B. Chance. In Section VI the enzymes of the plasma are discussed, and in Section VII the lipoproteins of blood and other tissues. D. M. Surgenor, M. J. Hunter and R. K. Brown, and J. S. Fruton are responsible for Section VI, and J. L. Oncley, F. R. N. Gurd, M. Macheboeuf, J. Folch-Pi, D. P. B a r , E. M. Rum, H. A. Eder, W. F. Lever, and N. A. Hurley for the section on lipoproteins. The paucity of exact knowledge with respect to the presence of lipids in combination with protein makes this section pilrt.icularly welcome. With the exception of the charts on pages 126 and 127 which should be laheled as to the proteins they represent, the chapters are adequately illustrated with figures and tables.

ship of these to a cycle of reproduction. J. C. Cam brings out some outstandine features of work on tumor viruses. F. K.

ends of most of the papers, there are discussion questions and comments. Some of the discussions are both amusing and cagent, others are dull and seemingly irrelevant. Certainly, anyone actively interested in the field of virus research will want to browse through this book.

F. A. CAJORI

U ~ m e n s r r ror C o ~ o n ~ o8 ac x o o ~or M E D ~ C W E D E N V E COLOR*^^ ~.

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INTERNATIONAL COMMITTEE OF ELECTROCHEMICAL THERMODYNAMICS AND KINETICS (2 VOLUMES) :

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THE NATURE OF VIRUS MULTIPLICATION

Edited by Sir Paul Fildes and W. E. Van Heyningen, Sir William Dunn School of Pathology, University of Oxford. Cambridge University Press, New York, 1953. 320 pp. 76 figs. 18 tables. 16 X 25 cm. $6.50. Tnrs hook contains the 16 papers which formed a basis for discussion at the Second Symposium of the Society for General Miorobiology held at Oxford University in April, 1952. The binding and cover of the hook are of an economy grade, hut are doubtless adequate for a work of this type in which the contents, owing to rapid developments, become obsolete relatively soon. To almost anyone concerned, it will be apparent that the topic for discussion, which has become the title of the book, should more precisely have been "Speculations on the Nature of Virus Multiplication," for the various authors obviously leaned heavily on conjecture and surmise for went of direot evidence. The material as a. whole seems to paint up the need for a more solid chemical and physical basis far some of the absorbing biological phenomena. which have been observed in the past ten years. Granted then, that no one will buy the boi kexpeeting to learn the secret of virus multiplication, it om he said that the volume does contain some excellent ~coounts of current ideas about virus multiplication, and that these ideas are based on the experimental results of a representative group of virrls experts. H. Chantrenne discusses the uncertainties of protein synthesis and summssizos current postulates m d clues. F. C. Bawden and N. W. Piriereiterate a number of their favorite conceptions of the nature of viruses and summon recent evidence from plant virus work to support their contentions. D. J. Bauer makes a critical survey of the status of enzymic activities associated with various animal viruses. Roy Markham eves a si~nificantevaluation of the role of nucleic acids in plant viruses based on chemical and physical data. S. E. Luris gives an excellent summary and discussion of some highlights of recent bacteriophage experiments. J. S. K. Boyd considers the relabion of mutation to lysogenicity in haoteriophages from 8. refreshingly unorthodox point of view. A. Lwoff presents an elaborate fabrication of ideas concerning the nature of viruses and virus renraluction hased on lysogenicity and other phenomena observed nith certain bacteriophages. R. Lnterjet describes some applications of radiohiologicd techniques to the study of phage reproduction. Fildes, Kay and Jaklik emphasize the importance of divalent ions, particularly Ca, in the phenomena of phage reproduction. Sven Gard attempts to eluoidate the reproduotive process in the influenza virus system by a mathematical manipulation of infectivity data. L. Hoyle speculate^ on the nature of virus reproduction using influenea as a model. T. H. Flewett describes attempts made to see influenza and fowl plague viruses in thin tissue sections employing electron microscopy. F. Fulton tries to adapt the binmy fission process to virus mdtiplication. G. R. Bergold discusses the unusual forms observed with some insect virusen and the ~ossihlerelation-

Proceedings of the IInd Meeting, Milan, 1950. Libreria Editrice Politccnica, Cesare Tamburini, Milan, 1951. m i 406 pp. Illustrated. 17.5 X 24.5 cm. L. 3800.

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Proceedings of the IIIrd Meeting, Beme, 1951. Edited by Car10 Manfredi, Vide Papioiano, Milan, 1952. wi 495 pp. Illuatcated. 17.5 X 24.5 om. L. 8000.

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TEE~E two volumes contain ahout eighty papera presented at meetings held a t Milan, Italy, in 1950 and Berne, Switzerland, in 1951. Soientists from Germany, Belgium, France, Italy, Norway, Sweden, Switzerland, Netherlands, Great Britain, Canada, and the United States contributed to one or another of the subjects: Electrode Potentiala, Kinetic Processes at Electrodes, Applications to the Study of Corrosion, Applications to General and Analytical Chemistry, Polarography, Electrical Double Layer and Nomenelrtture and Fundamental Electrochemical Definitions. The contents of most of the papers presented are theoretical and express the individual opinions of their authors at the times of the meetings. Indeed, as-stated in the prefaces, the purpose

conhiu stimulating contributions and are of considerahle value if one wishes to know current European thinking in this field. HERBERT 8. HARNED Y A L E UY~VERBITY

New HAYEN.C O N N E ~ I C O T

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MICROWAVE SPECTROSCOPY

her Gordy, Professor of Physics, Duke University; William V. Smith, Professor of Physics, University of Delaware; and Ralph F. Trambarulo, Assistant Professor of Physios, Pennsylvania State College. John Wiley & Sons, Inc., New York, 1953. xii 445 pp. Many figures and tables. 16 X 23.5 cm. $8.

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Mlc~owavEspectroscopy is one of the new and exciting experimental techniques that have appeared in the field of chemical physics since the last war. The development of radar opened for research a new range of the electromagnetic spectrum, and has made possible investigations of the low-lying energy levels existing in solid, liquij, and gaseous states of matter. Since 1946 the reports of this research have heenmainly carried in such journals a8 Physical Reuieur, Proceedings of the Physical Soeiel?, (Londa), and the Journal of Chemical Physics, but now Professors Walter Gordy, William V. Smith, and Ralph F. Trembarulo have written the first book in this field. dnder the title of "Microwave Spectroscopy" the authors discuss moleculrtr rotation spectroscopy, pure nuelem quadrupole spectroscopy, paramagnetic resonance, ferromqnetie resonance, and other miarowave absorption phenomena.