THESYNTHESIS OF DESOXYCANTHARIDINE
Nov., 1941
given 2.3 cc. pci kilo; after chlorination, the product killed 4-Chloro-6-nhexoyl-o-cresol a t 8.6 cc. per kilo. The unchlorinated ortho isomer was lethal for half of the animals a t 4.0 cc. per kilo; after 4-Chloro-6-nhexoyl-m-cresol chlorination the product was slightly less toxic a t 4.5 cc. 2-Chloro-B-nper kilo. For rats, the order of toxicity was similar escepl hexoyl-p-cresol that the unchlorinated para compound was most toxic. Detailed pharmacological reports will he published else- 4-Chloro-6-nhexyl-o-cresol where.20 4-Chloro-B-nTABLE V hexyl-m-cresol CHLORINE CONTENTS O F CHLOROTOLYL E-CAPROATES, 6-nI%EXOYLCHLOROCRESOLSAND ~-~-HExYLCHLOROCRESOLS2-Chloro-6-nhexyl-p-cresol --Chlorine, %Compounds
Formula
Calcd.
ClsH1702Cl
