The Swern Oxidation: Development of a High-Temperature

A Mild and Efficient Alternative to the Classical Swern Oxidation

Read OnlinePDF (42 KB) ... The Journal of Organic Chemistry 2012, 77 (2) , 929-937. .... Metal free visible light driven oxidation of alcohols to carbonyl derivatives using 3 ... Kumkum Srivastava, Sunil K. Puri, Brijesh Kumar, Prem M. S. Chauhan. ..

Investigation of the MoffattâSwern Oxidation in a Continuous Flow

Apr 30, 2008 - (7, 8) Oxidation of the alcohols 4g, 4 h, and 4i in batch experiments showed that addition of DIPEA at 20 Â°C results in a similar conversion when DIPEA was added at â70 Â°C, indicating that the ..... This paragraph is present in the

The Swern Oxidation - American Chemical Society

Jun 10, 2008 - The Dow Chemical Company, Midland, Michigan 48674, U.S.A.. Abstract: The Swern oxidation has been widely exploited for the oxidation.


notwithstanding the availability of many preparative methods, the restrictions that accompany some of them make new, mild, and selective procedures highly ...


Carbonyl compounds are of great importance as inter- mediates to prepare other functional groups in organic synthesis. In particular, aldehydes and N-protected.

Application of the Swern oxidation to the manipulation of highly

77130-01-9; 8, 96150-65-1; 10, 96129-57-6; 11, 96150-66-2; tri- ... ( NMR) spectra were recorded at 90 MHz. Chemical shifts are ... reported as follows: chemical shift (multiplicity, integrated in- tensity ..... 1320, 1210,1100, 860, 840 cnT1;. NMR .

Modification of the Swern Oxidation: Use of Stoichiometric Amounts of

Readily available 6-(methylsulfinyl)hexanoic acid (1) is employed as a substitute for DMSO in Swern oxidation reactions using oxalyl chloride to smoothly ...

Modification of the Swern Oxidation: Use of Stoichiometric Amounts of

The resulting 6-(methylthio)hexanoic acid (2) is easily separable by aqueous ... The Swern Oxidation: Development of a High-Temperature Semicontinuous ...

Mechanism of the Swern Oxidation - American Chemical Society

Nov 2, 2010 - Thomas Giagou and Matthew P. Meyer*. School of Natural Sciences, University of California, Merced, P.O. Box 5200 North Lake Road, Merced,.

Mechanism of the Swern Oxidation: Significant Deviations from

Nov 2, 2010 - School of Natural Sciences, University of California, Merced, P.O. ... to a significant degree at the temperatures at which the Swern oxidation is ...

The Swern Oxidation: Development of a High-Temperature

Recommend Documents