Subscriber access provided by Stony Brook University | University Libraries
Surfaces, Interfaces, and Applications
Ultrasensitive Au Nanooctahedron Micropinball Sensor for Mercury Ions Zhanxin Duan, Xingang Zhang, Tianyu Ye, Xiaolei Zhang, Shilian Dong, Jing Liu, Xiangheng Xiao, and Changzhong Jiang ACS Appl. Mater. Interfaces, Just Accepted Manuscript • DOI: 10.1021/acsami.8b04414 • Publication Date (Web): 06 Jul 2018 Downloaded from http://pubs.acs.org on July 6, 2018
Just Accepted “Just Accepted” manuscripts have been peer-reviewed and accepted for publication. They are posted online prior to technical editing, formatting for publication and author proofing. The American Chemical Society provides “Just Accepted” as a service to the research community to expedite the dissemination of scientific material as soon as possible after acceptance. “Just Accepted” manuscripts appear in full in PDF format accompanied by an HTML abstract. “Just Accepted” manuscripts have been fully peer reviewed, but should not be considered the official version of record. They are citable by the Digital Object Identifier (DOI®). “Just Accepted” is an optional service offered to authors. Therefore, the “Just Accepted” Web site may not include all articles that will be published in the journal. After a manuscript is technically edited and formatted, it will be removed from the “Just Accepted” Web site and published as an ASAP article. Note that technical editing may introduce minor changes to the manuscript text and/or graphics which could affect content, and all legal disclaimers and ethical guidelines that apply to the journal pertain. ACS cannot be held responsible for errors or consequences arising from the use of information contained in these “Just Accepted” manuscripts.
is published by the American Chemical Society. 1155 Sixteenth Street N.W., Washington, DC 20036 Published by American Chemical Society. Copyright © American Chemical Society. However, no copyright claim is made to original U.S. Government works, or works produced by employees of any Commonwealth realm Crown government in the course of their duties.
Page 1 of 23 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
ACS Applied Materials & Interfaces
Ultrasensitive Au Nanooctahedron Micropinball Sensor for Mercury Ions Zhanxin Duan#, Xingang Zhang#, Tianyu Ye, Xiaolei Zhang, Shilian Dong, Jing Liu, *
Xiangheng Xiao and Changzhong Jiang Department of Physics and Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, Hubei Nuclear Solid Physics Key Laboratory and Center for Ion Beam Application, Wuhan University, Wuhan 430072, P. R. China KEYWORDS: Au nanooctahedron, surface-enhanced Raman Scattering, plasmonic micropinball, mercury detection
ABSTRACT: Mercury ion (Hg2+) is one of the most toxic heavy metal which has severe adverse effects on environment and human organs even at very low concentrations. Therefore, highly sensitive and selective detection of Hg2+ is desirable. Here, we introduce plasmonic micropinball constructed from Au nanooctahedron as a 3D SERS platform, enabling ultrasensitive detection of trace Hg2+ ions. Typically, strong SERS signals could be obtained when the single-stranded DNA structure converts to the hairpin structure in the presence of Hg2+ ions, due to the formation of thymine (T)-Hg2+-T. As a result, the detection limit of Hg2+ ions is as low as 1 × 10-16 M, which is far below compared with these reported for conventional analytical strategies. Moreover, in order to achieve rapid multiple detection, we combine the micropinball sensors with microflow tube online detection. Our platform prevents cross-talk and tube contamination, allowing multi-assay analysis, rapid identification
ACS Paragon Plus Environment
ACS Applied Materials & Interfaces 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60
and quantification of different analytes and concentrations across separate phases. 1.
INTRODUCTION Mercury from emissions is gradually accumulating in the human body through
food and drinking water.1-3 Some terrible disease can be caused by the accumulation of mercury in the body, such as the damage to the brain and the degeneration of human senses.4-8 Thus, developing a sensitive and selective method for the detection of Hg2+ ions is necessary. So far, some manners have been developed for the detection of Hg2+, which is based on resonance,9 absorption spectroscopy,10, 11 fluorescence12 and biosensor.13-18 In general, traditional analytic strategys are rapid and low-cost.19-21 However, the shortcoming of these methods including cross-interference, or lack of sensitivity.22-24 Compared with these methods, surface-enhanced Raman spectroscopy (SERS) has drawn much attention due to its superior sensitivity and specificity. Up to now, several strategies of SERS sensors have been recorded for the capture of Hg2+ ions.25, 26 In our previous work,27 Au TNAs/graphene/Au NP sandwich structure also acts as SERS platforms for the detection of Hg2+. Although various strategies have been used to improve SERS sensitivity, for these works, there still remain major challenges for accurate, specific, and reliable detection of Hg2+ ions at sub-femtomolar levels (
