Ultrasensitive Detection of Dopamine Using a Carbon Nanotube

Ultrasensitive Detection of Dopamine Using a Carbon Nanotube Network Microfluidic ... †Department of Chemistry and ‡School of Engineering, Univers...
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Ultrasensitive Detection of Dopamine Using a Carbon Nanotube Network Microfluidic Flow Electrode Siriwat Sansuk,† Eleni Bitziou,† Maxim B. Joseph,‡ James A. Covington,‡ Martyn G. Boutelle,§ Patrick R. Unwin,† and Julie V. Macpherson†,* †

Department of Chemistry and ‡School of Engineering, University of Warwick, Coventry, CV4 7AL, United Kingdom Department of Bioengineering, Imperial College London, London, SW7 2AZ, United Kingdom

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ABSTRACT: The electrochemical measurement of dopamine (DA), in phosphate buffer solution (pH 7.4), with a limit of detection (LOD) of ∼5 pM in 50 μL (∼ 250 attomol) is achieved using a band electrode comprised of a sparse network of pristine single-walled carbon nanotubes (SWNTs), which covers