Unimolecular Polymeric Janus Nanoparticles: Synthesis, Self

Self-Assembly and Applications ... The evolution of self-assembly morphology is studied by transmission electron Microscopy (TEM) and atomic force...
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Unimolecular Polymeric Janus Nanoparticles: Synthesis, Self-Assembly and Applications Lei Zhu, Department of Macromolecular and Chemical Science and Engineering, Case Western Reserve Univ., OH, 44106-7202 Micelles of cationic amphiphilic triblock copolymer, PS-b-QP2VP-b-PEO, can complex with different types and lengths of DNA in aqueous solution, including oligomeric single-stranded and double-stranded DNA and long chain single-stranded DNA. The evolution of self-assembly morphology is studied by transmission electron Microscopy (TEM) and atomic force microscopy (AFM).

200 base unit ssDNA complex With cationic triblock copolymer

26 base pair dsDNA cationic triblock copolymer 26 base unit ssDNA

Increasing DNA content