Author Index Bakke, J. E., 301 Bergman, Ake, 124 Caldwell, John, 2 Chang, M. J . W., 214 Dorough, H. Wyman, 242 Edwards, Valerie T., 322 F e i l , V. J . , 177 Fenselau, Catherine, 159 Fentiman, A. F., J r . , 214 Haggerty, G. C , 214 Hutson, David H., 204,322 James, Margaret 0., 29 Kaneko, Hideo, 268
Lamoureux, G. L., 62 Leighty, E. G., 214 Meerman, John H. N., 282 Miyamoto, Junshi, 268 Muecke, W., 108 Mulder, Gerard J . , 282 Okuno, Yasuyoshi, 268 Quistad, Gary B., 204,221 Rusness, D. G., 62 van den Goorbergh, Ans M., 282 Webb, John D., 242 Wilkinson, C. F., 48 Y e l i e t , Lauren, 159
Downloaded by 80.82.77.83 on May 29, 2018 | https://pubs.acs.org Publication Date: January 24, 1986 | doi: 10.1021/bk-1986-0299.ix001
o
Subject Index A
Acetaminophen bioactivation, 246 glutathione conjugation, 305 glutathione d e t o x i f i c a t i o n , 250 overdose-induced l i v e r necrosis, 249f N-Acetyl-cysteine conjugates, synthesis, 136-144 Acetylated amino acid, epoxide derived, 225f Acetylation c l a s s i f i c a t i o n of the major conjugation reactions, 6t mammals, discussion, 13-15 novel polar xenobiotic conjugates i n animals, 230 species defects, 14,20t various substrates, comparison among carnivores, 21t N-Acetyltransferase acetylation, 14 taurine, assay for measuring, 43 Acidic amidates, novel polar xenobiotic conjugates i n animals, 230 Acids chain extension, novel l i p o p h i l i c conjugates, 205 f a t t y , acylation of xenobiotic alcohols, 215 forming amides, 225f
Ac id s—Continued natural, and xenobiotics i n plants, esters derived from, 211f xenobiotic, hybrid glycerides from, 207f Acifluorfen, metabolism, by homoglutathione conjugation, 83 Acylation of xenobiotic alcohols, metabolic pathway for drug retention, 214-219 Addition reactions, synthesis of glutathione, cysteine, and N-acetyl-cysteine conjugates, 142 Adduct formation by the sulfate conjugate of N-hydroxy-2AAF, mutual effects of glutathione and RNA, 286t Aglycones fish in v i t r o metabolism, 33 in vivo metabolism, 30-33 Koenigs-Knorr-type synthesis, 128t structure, importance to t o x i c i t y of a glycoside, 324 Alanine and putrescine conjugates, 234f Alcohols sulfate conjugation, 12t xenobiotic acylation of, metabolic pathway for drug retention, 214-219 formation of /3-D-glucoside i n insects, 51f
342
Paulson et al.; Xenobiotic Conjugation Chemistry ACS Symposium Series; American Chemical Society: Washington, DC, 1986.
