A Synthetic Approach to Cephams - The Journal of Organic Chemistry

DOI: 10.1021/jo01343a503. Publication Date: May 1966. ACS Legacy Archive. Cite this:J. Org. Chem. 1966, 31, 5, 1635-1637. Note: In lieu of an abstract...
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MAY1966 The infrared spectrum (potassiumbromide disk) showed strong absorption a t 1025 and 1037 em-' (sulfoxide region) and a t 967 cm -l. Cyclization of Propenylcysteine Sulfoxide to Cycloal1iin.-A solution of 120 mg of the amino acid in 80 ml of 1 N ammonium hydroxide was allowed to stand 4 days when it was concentrated in vacuo t,o a crystalline solid. The solid was dissolved in 5 ml of water, 5 ml of 2 N hydrochloric acid was added, and the solution was concentrated in vacuo a t