Anal. Chem. 1994,66, 1231-1235
Amperometric Glucose Sensors Based on Immobilized Glucose Oxidase-Polyquinone System Takahlko Kaku,t Hlroko I. Karan,* and Yoshlyukl Okamoto'it Department of Chemistry and Polymer Research Instltute, Po&technic University, 6 Metrotech Center, Brooklyn, New York 1 120 1, and Department of Physical Sciences and Computer Science, Medgar Evers College, City University of New York, Brooklyn, New York 11225 Non-cross-linked and also cross-linked poly(ether amine quinone)s were prepared and tested for their efficiency as electron-transfer relay systems in amperometric glucose biosensors. Cyclic voltammetry and constant applied potential measurements showed that poly(ether amine quinone) relay systems efficiently mediated electron transfer from reduced glucose oxidase to a conventional carbon paste electrode. Sensors containing these relay systems respond rapidly to low (
