Antihypertensive Agents as Seen by the Clinician

in cardiac output (Figure 1) severely limit the clinical use of this drug. ... potassium losses with resultant hypokalemia, and hyperuricemia. Hyperur...
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Clinical Review & Education

JAMA Clinical Guidelines Synopsis

Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults Adam S. Cifu, MD; Andrew M. Davis, MD, MPH

GUIDELINE TITLE 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults DEVELOPER American College of Cardiology (ACC) and American Heart Association (AHA) RELEASE DATE November 13, 2017 PRIOR VERSION 2003 (Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure [JNC 7])

a. Many nonpharmacologic interventions that are effective in lowering BP are recommended for people with elevated BP or hypertension (strong recommendation; high-quality evidence). b. Blood pressure–lowering medication is recommended for patients with clinical CVD or an estimated 10-year atherosclerotic CVD (ASCVD) risk of 10% or higher who have a systolic BP (SBP) of 130 mm Hg or higher or a diastolic BP (DBP) of 80 mm Hg or higher (strong recommendation; high-quality evidence [for SBP] and expert opinion [for DBP]). c. For patients with no history of CVD and an ASCVD risk of less than 10%, BP-lowering medication is recommended for patients who have an SBP of 140 mm Hg or higher or a DBP of 90 mm Hg or higher (strong recommendation; low-quality evidence).

3. Management

FUNDING SOURCE ACC/AHA TARGET POPULATION Patients with or at risk of developing cardiovascular disease (CVD)

MAJOR RECOMMENDATIONS

1. Diagnosis a. Blood pressure (BP) should be categorized as normal (