Deuterium Isotope Effect in Chloramphenicol Action In

Several hypotheses have been developed to explain the mode of action of chloramphenicol in bacterial cells.' * Evidence is increasing that chloramphen...
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Journal of Medicinal Chemistry, 1971, VoZ. 14, No. 10 931

DEUTERIOCHLORAMPHENICOLS spectrum, major signals a t mlc 197, 182, 155, 140, 127, 125, 113, 111, 98, and 97. Anal. (ClOHlQN30) C, H, N.

Acknowledgment.-The authors thank Drs. A. B. Sen and R. I