AWARDS
Biological Division awards to Goeddel and Tjian David Goeddel, staff scientist at Genentech Inc., will receive the 1984 Eli Lilly Award in Biological Chem istry. The award consists of a bronze medal and $2000 honorarium. It is administered by the ACS Division of Biological Chemistry and is spon sored by Eli Lilly & Co. Goeddel received his B.A. from the University of California at San Diego in 1972, and his Ph.D. from the Uni versity of Colorado, Boulder, in 1977. He joined Genentech in 1978. His graduate thesis work involved the chemical synthesis of the lac opera tor, both wild type and with muta tions at virtually every position, and the physico-chemical analysis of the interaction of those synthetic prod ucts with the lac repressor. This work covered many disciplines and was very productive, resulting in 12 publications. Goeddel's subsequent work has centered on the cloning of genes for biologically active peptides both in Escherichia coli and in yeast. Of great importance has been the develop ment of procedures leading to very high levels of expression of the pro tein products. This work has includ ed the successful production of human insulin, human growth hor mones, human leukocyte interferon, human fibroblast interferon, and thymosin a.\. His isolation and char acterization of the elusive gamma interferon was a masterful tour-de force. While providing the major intel lectual leadership for all of these projects, Goeddel has also assembled a research group at Genentech which is considered one of the finest in the field. The active publication policy and openness of this group in dis cussion and collaboration with others has had an enormous impact world wide on research in this area. Goed del has managed to provide proce dures and products of broad use to both the scientific and industrial sectors while maintaining a strong effort in basic research at the very cutting edge of this field. Robert Tjian, biochemistry professor at the University of California, Berkeley, will receive the 1984 Pfizer Award in Enzyme Chemistry. The
Goeddel
Tjian
award of $2000 and a gold medal is given annually by the ACS Division of Biological Chemistry, and is sponsored by Pfizer's Central Re search Division. Tjian received his A.B. from Berkeley in 1971 and his Ph.D. from Harvard in 1976. As an undergrad uate he carried on honors research in the area of enzyme mechanisms, and then spent a year in Oxford deter mining the x-ray crystallographic structures of some lyzozyme-ligand complexes. His graduate work at
Harvard centered on RNA polymer ase and the control of gene expres sion during sporulation in Bacillus subtilis. Tjian's major and continuing studies of the virus SV 40 began during a postdoctoral period at Cold Spring Harbor. He was the first to purify to near homogeneity the Τ antigen and, with a nuclease injec tion technique developed in collab oration with A. Graessman, showed that this antigen was responsible for inducing cellular DNA synthesis. Later Tjian discovered that Τ antigen interacts with three closely spaced tandem recognition sequences in duplex DNA. His studies on control of SV 40 transcription mark one of the first successful attempts at iden tifying an RNA polymerase II control site in vitro and in vivo. Tjian went on to identify a series of factors affecting transcription. Spe cifically, he discovered and isolated a factor that can discriminate be tween different RNA polymerase II promoters. During his studies on
Piperylene
CH
CH,
v... CH
GET TACKY Resins made from Conoco Piperylene Concentrate.They're a tactful, in expensive alternative to natural rosins for use in fillers, tackifiers and linear aliphatic resins. For more information,write Manager, Industrial Chemicals,Conoco Chemicals, P.O. Box 19029, Houston,Texas 77224.
(conoco) Conoco Chemicals CIRCLE 9 ON READER SERVICE CARD November 14, 1983 C&EN
55
Awards regulatory proteins, Tjian pioneered the construction of novel adenovirus SV 40 hybrid vectors as the basis for an efficient procedure for overpro ducing proteins in a eukaryotic ex pression system. Tjian has skillfully
Stork has received honorary degrees from Lawrence University (D.Sc, Hon., 1961), and Univ. Pierre et Marie Curie, Paris (D.Sc, Hon., 1979). His other hon ors include the ACS Award in Pure Chemistry (1961), Baekeland Medal (1961), Harrison Howe Award (1962), Edward Curtis Franklin Memorial Award (1966), ACS Award for Creative Work in Synthetic Chemistry (1967), SOCMA Gold Medal (1973), Roussel Prize (1978), Nichols Medal (1980), Arthur C. Cope Award (1980), Edgar Fahs Smith Award (1982), Willard Gibbs Medal (1982), Na tional Academy of Sciences Award in Chemical Sciences (1982), and the Na tional Medal of Science Award (1983). He was elected to the National Academy of Sciences in 1961 and to the American Academy of Arts & Sciences in 1962. Stork's current research interests in clude the total synthesis of complex nat ural products, including a wide variety of antibiotics, alkaloids and steroids, and the development of new synthetic methods. Stork will receive the Pauling Award at an evening banquet in Corvallis, Ore., on Nov. 19, at which Prof. Linus Pauling will be the guest of honor.
used a wide variety of disciplines in these pioneering advances. He has established himself as a leader in this area of molecular biology involving the most complex and intricate en zymatic systems.
18th Pauling gold medal award to Gilbert Stork Gilbert Stork, professor of chemistry at Columbia University, will receive the 18th Pauling Award Medal of the ACS Puget Sound and Oregon sections. The annual award honors an individ ual who has made outstanding con tributions to chem istry that have merited interna tional recognition. Stork's research and teaching, which has spanned more than 35 years, has made a significant and dra matic impact on organic chemistry. His pioneering research in the total synthesis of a variety of complex natural products
and the development of new synthetic methods has been a blend of sound un derstanding, perceptive insight, and creativity. Stork was born in 1921 in Brussels, Belgium, and spent his childhood in Paris. At the beginning of World War II his family came to the U.S. He received a B.S. degree in 1942 from the University of Florida. His graduate work was carried out with S. L. McElvain at the University of Wisconsin where he received his Ph.D. in 1945. After a stay at Harvard, he joined the department of chemistry at Columbia University in 1953. He was promoted to professor in 1967, and served as chairman of the department of chemistry (19731975). He is currently Higgens Professor of Chemistry.
READ JUST WHAT YOU NEED C h e m i s t s a^rcc t h a t one h o u r in the l i b r a r y can save weeks in the l a b . But w h y s p e n d even a n h o u r in tin 4 l i b r a r y w h e n y o u c o u l d be r e a d i n g ( A S K L K C T S ? E a c h of the 133 ( A S E L E C T S c u r r e n t - a w a r e n e s s p u b l i c a tions cuts t h r o u g h stacks o f scientific l i t e r a t u r e a n d b r i n g s y o u just the p o r t i o n relevant to y o u r w o r k . T h a t ' s w h y the w o r l d ' s chemists are r e a d i n g ( ' A S E L E C T S . A r e you? I o f i n d o u t how y o u c a n «jet out o f the l i b r a r y a n d b a c k to the l a b — f o r less t h a n S 2 . 0 0 a w e e k ! — s e n d f o r o u r 1(>83 catalog.
CA SELECTS Tell me more about CA SELECTS! Send me your 1983 catalog.
Name _ Addm»s
CA SELECTS
®
Current-Awareness Publications from Chemical Abstracts Service 56
November 14, 1983 C&EN
Return to Chemical Abstracts Service Marketing Dent. 30783 P.O. Box 3012 Columbus. OH 43210 I S A
( \ S h ,κΙίΜΜΜί,ηΙ III.· \ΜΙΓΙΊ..Η|( III· II11. i. Ι Ν M I.I V .
Calls for nominations Nominations are solicited for the Advancement of Application of Agricultural & Food Chemistry Award administered by the Agricultural & Food Chemistry Division and sponsored by International Flavors & Fragrances Inc. The award, consisting of $2000, an inscribed certificate, and travel allowance, recognizes outstanding contributions to pure and/or applied agriculture and food chemistry. A nominee must have made (1) outstanding application of chemistry to the solution of agricultural or food problems of importance to the nourishment and health of mankind, or (2) outstanding contribution to the advancement of pure and/or applied agricultural and food chemistry. Nominations should be submitted to: Constance Kies, Dept. of Food & Nutrition, University of Nebraska, Lincoln, Neb. 68583 not later than Jan. 1, 1984. The ACS History of Chemistry Division is seeking nominations for the 1984 Dexter Award sponsored by Dexter Chemical Corp. The award honors outstanding accomplishment in the history of chemistry, and consists of $1000. Nominations should include a cover letter containing an assessment of the nominee's contributions to the field, vitae, and bibliography of publications. The document should be sent to: Robert H. Goldsmith, Secretary-Treasurer History Division, Anne Arundel Hall 201 A, St. Mary's College of Maryland, St. Mary's City, Md. 20686. The deadline for nominations is Jan. 1, 1984. The ACS Division of Colloid & Surface Chemistry is soliciting nominations for the 15th Victor K. LaMer Award for outstanding dissertation research in colloid and surface science. Selection will be based on nominating letters and a Ph.D. thesis accepted by an American or Canadian university during the three-year period prior to Feb. 1, 1984. Deadline for nominations is March 1, 1984. Nominating letters and /or requests for additional information should be sent to: Raymond MacKay, Chairman of the Award Committee, Chemical Branch, Research Division, Chemical R&D Center, Aberdeen Proving Ground, Md. 21010. The Central Wisconsin Section requests nominations for the F. J. Zimmermann Award in Environmental Science. The $1000 award, which is sponsored by Zimpro Inc., recognizes scientific work having a significant impact on the protection of the environment. Any scientist, without regard to ACS membership, residing in the U.S. is eligible for nomination. Nominations should include a bio-
graphical sketch, list of publications, specific identification of the work on which the nomination is based, and an evaluation and appraisal of the nominee's accomplishments. Nominating letters and/or additional information is available by writing to Leo A. Ochrymowycz, Chairman of the Awards Committee, Dept. of Chemistry, University of Wisconsin, Eau Claire, Wis. 54701, Tel. (715) 836-3500. Nominations are due no later than Feb. 1, 1984. The Coblentz Society is soliciting nominations for the following three awards: the Coblentz Award, Williams-Wright Award, and the Lippincott Award. The Coblentz Award, presented annually to recognize outstanding young spectroscopists under the age of 36, consists of $1000 plus a travel allowance. Nominations, which should include a detailed description of the nominee's accomplishments, a curriculum vitae, and supporting letters, should be sent to: Robin S. McDowell, Los Alamos Scientific Lab, Mail Stop J567, Los Alamos, N.M. 87545, Tel. (505) 667-7071, on or before April 30, 1984. The Williams-Wright award is pre-
sented annually at the Pittsburgh Conference to an industrial spectroscopist who has made significant contributions to vibrational spectroscopy while working in industry. The work may include infrared and /or Raman spectroscopy, instrumental development as well as theory, and applications of vibrational spectroscopy. The prize includes $1000 plus a travel allowance to the Pittsburgh Conference. Nominations should be sent to: Peter Griffiths, Dept. of Chemistry, University of California, Riverside, Calif. 92521, Tel. (714) 787-4708, by the deadline of April 30, 1984. The Lippincott Award is given annually to an outstanding vibrational spectroscopist with no restrictions except that the winner be alive at the time of selection. The recipient of the medal must have made significant contributions to vibrational spectroscopy. The contributions may be theoretical or experimental, or both, and may have been made in the course of applied as well as basic research. Nominations should be submitted to: K. Narahari Rao, Department of Physics, 174 West 18th Ave., Columbus, Ohio 43210, Tel. (614) 422-6505. The deadline for receipt of nominations is Feb. 1, 1984.
Alkylstyrene/Indene My
SAVE A TREE
Conoco Resin Oil I I (Alkylstyrene/Indene Concentrate),a reactive H H H I mixture of C 8 to G10 aromatics,is an inexpensive alternative to natural rosins for rubber compounds,caulks, solvents and coatings. For more information,write our Manager, Industrial Chemicals, Conoco Chemicals Company, Post Office Box 19029, Houston,Texas 77224.
(conoco) Conoco Chemicals CIRCLE 10 ON READER SERVICE CARD November 14, 1983 C&EN
57
