Model reactions for the metabolism of thyroxine. II. Reaction of

triiodothyronine which in turn cleaves at thediphenyl ether linkage to form 3,5-diiodotyrosine, nonenzymic auto- xidations of 3 '-hydroxythyropropionic acid and of ...

May 1, 2002 - Gerhard Bringmann, Thomas Pabst, Petra Henschel, J rgen Kraus, Karl Peters, Eva-Maria Peters, David S. Rycroft, and Joseph D. Connolly.

Model reactions :ire prescuted for the biosynthetic scheme (equations 1-3) proposed by Johnson and Tewkesbury for. Sterically hindered analogs of the quinol ...

Thyroxine is formed in about 20% yield when. DIHPPA4 is permitted to react with DIT4 at room temperature in a neutral or slightly alkaline solution.5. Analogs of thyroxine are formed when in this reaction the amino acid is replaced with certain analo

Silver Ion-Mediated Coupling of 4-Bromo-2,6-di-tert-butylcycohexa-2,5-dienone with Phenols. Kanji Omura. The Journal of Organic Chemistry 1998 63 (26), ...

VI. Structural Requirements of Analogs of Diiodotyrosine in the Reaction with 4-Hydroxy-3,5-diiodophenylpyruvic Acid to Form Analogs of Thyroxine1,2.

Model reactions for the biosynthesis of thyroxine. Nonenzymic formation of 3,5,3'-triiodothyronine from 4-hydroxy-3-iodophenyl-pyruvic acid, 3,5-diiodotyrosine, ...

MATSUURA, KON, AND CAHNMANN. VOL. 29. Model Reactions for the Biosynthesis of Thyroxine. VII. Free Radicals Generated from 4-Hydroxy-3 ...

react with 3,5-diiodotyrosine at pH 8 at room temperature to form the corresponding hormones. This “coupling reac- tion” may be a nonenzymic model for the ...

of reactions represeiits a nonenzymic model for the ronversion of diiodotyrosine to thyroxine in aizio. The synthesis of various quinol ethers of type. IT7 from ...