1418
J. Org. Chem. 2002, 67, 1418
Additions and Corrections Vol. 66, 2001 Oscar Pa` mies and Jan-E. Ba1 ckvall. Dynamic Kinetic Resolution of β-Azido Alcohols. An Efficient Route to Chiral Aziridines and β-Amino Alcohols.
Page 4022. The sentence “The viability of this strategy is illustrated by the practical syntheses of (S)-propanolol I...” should be “The viability of this strategy is illustrated by the practical syntheses of the enantiomers of (S)propranolol I...”. Page 4023. Structures 2a-g and 1a should be drawn as follows:
Page 4024. The absolute configuration of the products 2a-g and 1a-g should be inverted (i.e., the S enantiomer was formed for compounds 2a-e and the R enantiomer for compounds 2f and 2g). Therefore, in column 1, the sentence “...the in situ hydrolysis of acetate 2c...” should be “the in situ hydrolysis of acetate 2c with LiOH in methanol gave quantitatively (S)-β-azido-R-(4methoxyphenyl)ethanol (S)-1c, a precursor of (S)-denopamine, in essentially enantiomerically pure form (ee >99%)”. Page 4024. Scheme 2 should be drawn as follows: Scheme 2. Synthesis of (R)-Propranolol Ia
Page 4025. A mistake in the sign of the [R]21D of compound I has been detected. The correct [R]21D is + 24.3. Therefore, the absolute configuration of compound I is R. “(S)-Propanolol” should be “(R)-Propranolol” and “(S)-2g” should be “(R)-2g”. JO0129531 10.1021/jo0129531 Published on Web 01/15/2002
