Glycerine is the Solvent - C&EN Global Enterprise (ACS Publications)

Nov 5, 2010 - Advertisements that appeared within the print issues of Chem. Eng. News have been included in the C&EN Archives to provide a ...
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em Sow E ute For 2 6 y e a r s S h a r p & Dohme Inc. has used U.S.P. Glycerine as the solvent for h e x y l r e s o r c i n o l in its f a ­ mous "S.T. 3 7 Antiseptic So­ lution." Because S.T. 37 is a p p l i e d d i r e c t l y to open wounds and t h e delicate mucous surfaces of the throat and mouth, the sol­ vent must be non-toxic, noni r r i t a t i n g a n d harmless. U.S.P. G l y c e r i n e fits a l l of these important require­ ments. It also adds body to the preparation.

Glycerine is an excellent solvent for a variety of substances —iodine, bromine, boric acid, phenol, thymol, alkaloids, hexylresorcinol, to name just a few. It is also a plasticizer for jelly and emulsion-type compounds. Its viscosity and suspending power make it a good vehicle for substances which otherwise would settle,out. More than 50 per cent of all liquid medications compounded by the druggist are reported to contain Glycerine. Surveys have shown that one out of four doctor's prescriptions require it. T h e reason? Glycerine can act not only as a solvent, but also as a humectant, demulcent, emollient, sweetener, antiseptic, or bodying agent. It has been safely used for years, internally and externally. T h e r e is no single substitute that combines all of Glycerine's physical and chemical properties. A handy 16-page booklet, "Why Glycerine for Drugs and Cosmetics?" will review these properties for you in detail. For your copy, write Glycerine Producers' Association, 295 Madison Avenue, New York 17, Ν. Υ.

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