Headgroup-Dependent Membrane Catalysis of ApelinReceptor


Jul 6, 2009 - converged and mirroring the observation of highly defined φ ... a Classification of NOE restraints using CYANA, LA Systems,. Tokyo, Jap...
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B , 2009, 113 (30), pp 10465–10471. DOI: 10.1021/jp904562q. Publication Date (Web): July 6, 2009. Copyright © 2009 American Chemical Society. * To whom ...

Jul 6, 2009 - Apelin is the peptidic ligand for the G-protein-coupled receptor APJ. The apelin−APJ system is important in cardiovascular regulation, fluid homeostasis, and angiogenesis, among other roles. In this study, we investigate interactions

A strategy to break the trade-off between laccase activity and. Page 3 of 28 ..... BPA removal. The pristine and biocatalytic membranes were respectively placed.

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with substrate analogues. Compound. Abbreviation. Source. Cofactor Resolution. Ordered. Reference. Comments. D-myo-inositol-1,4,5-trisphosphate. 1,4,5-IP.

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the remaining, catalytically active portion, Δ(1-132) PLC-δ, (75, PDB code 2ISD). The C2 domain was ..... hydrophobic character of this surface area are Tyr358, Phe360 and Trp555. All of these residues .... 380, 595-602. 16. Grobler, J. Α.

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Dec 15, 1998 - Log In Register .... of the inositol head group, whereas the 5-phosphoryl determines its precise orientation in the active site. ... identifies a hydrophobic ridge on the catalytic domain as a putative membrane penetration site.

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