J. Phys. Chem. B 1998, 102, 1649-1657
1649
Imaging the Molecular Dimensions and Oligomerization of Proteins at Liquid/Solid Interfaces Mark J. Waner,† Martha Gilchrist,† Melvin Schindler,‡ and Marcos Dantus*,† Departments of Chemistry and Biochemistry, Michigan State UniVersity, East Lansing, Michigan 48824 ReceiVed: October 2, 1997; In Final Form: December 10, 1997
Individual Concanavalin A (ConA) molecules have been imaged at the liquid/solid interface with an atomic force microscope (AFM). Three-dimensional sizing with very high resolution (