Marked Differences in Base Selectivity between DNA and the Free

DNA and the Free Nucleotides upon Adduct. Formation from Bay- and Fjord-Region ... Pages 884r885. Because of differences in column perfor- mance over ...
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Chem. Res. Toxicol. 2001, 14, 148

Additions and Corrections Marked Differences in Base Selectivity between DNA and the Free Nucleotides upon Adduct Formation from Bay- and Fjord-Region Diol Epoxides [Volume 13, Number 9, September 2000, pp 883-890] SREENIVASARAO VEPACHEDU, NAIQI YA, HARUHIKO YAGI, JANE M. SAYER*, AND DONALD M. JERINA Pages 884-885. Because of differences in column performance over time, only relative retention times were reproducible. On the Beckman column used for analysis of the BcPh DE reaction mixtures, the internal standard generally eluted between 18.5 and 19.6 min rather than at 21 min as stated. Elution orders for the tetraols were as follows. From BcPh DE-1: minor, trans tetraol; major, cis tetraol; standard. From BcPh DE-2: trans tetraol (exclusively formed); standard. On the VYDAC column used for analysis of the BaP DE reaction mixtures, the internal standard generally eluted between ∼13 and 16 min. The tetraols and thiolate adducts were consistently well-separated from the standard and from each other, with the following elution orders. From BaP DE1: minor, trans tetraol; major, cis tetraol; standard; thiolate adduct. From BaP DE-2: major, trans tetraol; minor, cis tetraol; thiolate adduct; standard. We thank David J. Johnson of the University of Guelph (Guelph, ON) for calling our attention to an internal inconsistency in our previously reported retention times. TX000493L 10.1021/tx000493l Published on Web 12/09/2000