Microfluidic Electroporative Flow Cytometry for Studying Single-Cell

Sep 18, 2008 - Microfluidic Electroporative Flow Cytometry for. Studying Single-Cell Biomechanics. Ning Bao, Yihong Zhan, and Chang Lu*. Department of...
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Anal. Chem. 2008, 80, 7714–7719

Microfluidic Electroporative Flow Cytometry for Studying Single-Cell Biomechanics Ning Bao, Yihong Zhan, and Chang Lu* Department of Agricultural and Biological Engineering, Weldon School of Biomedical Engineering, School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907 Biomechanical properties of cells yield important information on the disease state of cells such as transformation and metastasis. Screening of cells based on their biomechanical properties provides rapid tools for label-free diagnosis and staging of cancers. However, existent singlecell techniques for measuring biomechanical properties suffer from low throughput (