Chem. Res. Toxicol. 1993, 6, 168-173
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N-Nitroso-N-methylvinylamine:Reaction of the Epoxide with Guanyl and Adenyl Moieties To Yield Adducts Derived from Both Parts of the Molecule Osamu Okazaki,+Magnus Persmark, and F. Peter Guengerich* Department of Biochemistry and Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146 Received October 12, 1992
N-Nitroso-N-methylvinylamine was synthesized and treated with dimethyldioxirane to produce 1-(N-nitrosomethy1amino)oxirane.1-(N-Nitrosomethy1amino)oxiranehad a tl12 of